46 citations
,
May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
24 citations
,
February 2007 in “Hormone and metabolic research” The substance MK386 effectively blocked testosterone conversion and reduced cell growth in certain skin cells, but inhibiting 5α-reductase alone may not greatly improve acne.
March 2025 in “Molecules” Tectona grandis leaf extracts, especially with propylene glycol, may be promising for topical hair loss treatments.
December 2024 in “Journal of Pharmaceutical Research International” The gel effectively delivers dutasteride for hair loss treatment and remains stable for 90 days.
August 2024 in “Biomedical Journal of Scientific & Technical Research” Jute leaves may help reduce DHT levels, potentially aiding in conditions like hair loss and prostate issues.
May 2008 in “10th European Congress of Endocrinology” November 2025 in “Drug Testing and Analysis” Epristeride's metabolism involves key metabolites and proteins, affecting its use in doping tests.
8 citations
,
October 2020 in “Pharmaceutics” Dutasteride-loaded nanoparticles coated with Lauric Acid-Chitosan show promise for treating hair loss due to their controlled release, low toxicity, and potential to stimulate hair growth.
August 2025 in “ACS Omega” New compounds show promise as nonsteroidal treatments for hair loss.
Finasteride-loaded microemulsions, made with cinnamon oil, Tween20, propylene glycol, and water, can help maintain stemness of dermal cells, potentially aiding in hair regeneration.
9 citations
,
April 1970 in “Biochemical pharmacology” Stilbamidine and hydroxystilbamidine inhibit enzyme release from lysosomes and have effects similar to cortisol and chloroquine.
3 citations
,
April 2016 in “Research and reports in urology” The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.
December 2022 in “Scientific Reports” Compound 4 is a promising treatment for hair loss with low toxicity.
2 citations
,
April 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” The saw palmetto extract effectively inhibits an enzyme linked to prostate issues, showing promise for prostate health.
6 citations
,
October 1993 in “Endocrinology” Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.
13 citations
,
January 2015 in “Steroids” The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
6 citations
,
October 2023 in “Pharmaceuticals” Eclipta prostrata extract may help with memory and diabetes due to its antioxidant and enzyme-inhibiting properties.
258 citations
,
July 2005 in “Journal of lipid research” DGAT1 enzyme helps make diacylglycerols, waxes, and retinyl esters.
22 citations
,
February 2002 in “Planta Medica” Compounds from Angelica koreana roots, especially osthenol, could be effective for treating conditions like prostate disease and hair loss.
1 citations
,
January 2013 Glucosylceramides are essential for healthy skin and proper wound healing.
196 citations
,
May 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Sebocytes play a key role in controlling androgen levels in human skin.
4 citations
,
August 2018 in “International Journal of Current Microbiology and Applied Sciences” Eclipta prostrata leaves contain various compounds with medicinal properties.
June 2003 in “Obstetrical & Gynecological Survey” Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.
January 2014 in “HAL (Le Centre pour la Communication Scientifique Directe)” Chitosan-decorated carriers may improve topical finasteride delivery for hair loss treatment.
4 citations
,
October 1988 in “Clinics in Dermatology” Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.
August 2021 in “International Journal of Research in Dermatology” Amarantha hair oil contains β-sitosterol, which helps promote hair growth.
January 2026 in “Neurochemistry International” 24-Hydroxycholesterol reduces DHT formation in brain cancer cells, linking cholesterol and hormone metabolism.
2 citations
,
September 2023 in “Foods” Microcapsules and effervescent tablets make insect lipids easier to consume.
February 2025 in “Universidade Nova de Lisboa's Repository (Universidade Nova de Lisboa)”
5 citations
,
February 2010 in “Drug development and industrial pharmacy” Vesicles made of behenyltrimethylammonium chloride and stearic acid can triple the skin absorption of hinokitiol, which may help with hair growth.