6 citations
,
August 2009 in “Mini-reviews in Medicinal Chemistry” Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
31 citations
,
September 2020 in “Clinical endocrinology” Some antiandrogens may lower testosterone better than others, but it's unclear which is best for feminization in transgender women; more research is needed.
March 2016 in “The Journal of Urology” The discovery of 5α-reductase deficiency in guevedoces led to the development of important urologic medications.
88 citations
,
June 2016 in “Human Reproduction Update” New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.
May 2021 in “Journal of the Endocrine Society” A woman's severe hormone imbalance after menopause led to finding a rare ovarian tumor, treated by surgery.
35 citations
,
January 2005 in “Brain Research” Progesterone's anesthetic effects don't rely on progesterone receptors.
1 citations
,
October 2017 in “Elsevier eBooks” Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
33 citations
,
January 2016 in “Skin appendage disorders” The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.
20 citations
,
January 2007 in “Fertility and Sterility” A woman developed male traits from accidental contact with her husband's testosterone gel.
January 2002 in “Dialnet (Universidad de la Rioja)” Finasteride treatment makes the prostate look more like a healthy one.
Finasteride affects prostate development differently in male and female Mongolian gerbils.
22 citations
,
November 2018 in “Breast Cancer Research and Treatment” The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.
29 citations
,
April 2019 in “BMJ. British medical journal” Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.
1 citations
,
February 2008 in “Nature Clinical Practice Urology” Finasteride's sexual side effects may be due to nocebo effect.
January 2021 in “Figshare” Finasteride's molecular properties and active sites were identified using computational methods.
November 1990 in “Inpharma weekly” Flutamide effectively treated hair growth and related symptoms in women, with common side effects like dry skin and hot flushes.
1 citations
,
January 2003 in “Chinese Journal of Pharmaceuticals” A new method to make Finasteride is more cost-effective and yields 16%.
Use mild topical steroids to avoid side effects, especially in children.
3 citations
,
April 2012 in “Osteoporosis International” A woman experienced hair loss after taking strontium ranelate for osteoporosis.
38 citations
,
October 1996 in “Dermatologic Clinics” Certain hormone treatments can improve acne and related conditions in women.
7 citations
,
September 2023 in “Cancer Treatment Reviews” Managing side effects of endocrine therapy is crucial to improve adherence and survival in breast cancer patients.
2 citations
,
April 2023 in “Pharmaceuticals” Testosterone therapy for postmenopausal women appears safe and may protect against heart disease, but requires constant monitoring and more research for long-term effects.
August 2016 in “Journal of Investigative Dermatology” January 2012 in “Курский научно-практический вестник "Человек и его здоровье"” 5-alpha-reductase inhibitors can effectively treat benign prostatic hyperplasia.
13 citations
,
September 2011 in “International Urology and Nephrology”
March 2009 in “The Journal of Urology” Low dose finasteride causes only small changes in PSA levels in older men with BPH.
April 2014 in “Investigative Ophthalmology & Visual Science” 6 citations
,
October 2021 in “Brain Sciences” Dutasteride may help reduce brain inflammation and improve cognition.
80 citations
,
January 1988 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Spironolactone can cause side effects like irregular bleeding, but lower doses may reduce these effects and still improve hirsutism.
83 citations
,
November 2006 in “European Journal of Neuroscience” Progesterone protects rat brain cells by enhancing GABA A receptor activity.