October 2021 in “Journal of Investigative Dermatology” The study concludes that as skin matures from infancy to childhood, there are major changes in cell differentiation, stemness, and growth, leading to a stronger skin barrier in older children.
92 citations
,
May 2004 in “Journal of Investigative Dermatology” 2 citations
,
February 2025 in “Journal of Investigative Dermatology” Progenitor cells randomly decide their roles to maintain hair follicle growth.
14 citations
,
May 2022 in “Stem cell reports” The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
15 citations
,
June 2011 in “Journal of Investigative Dermatology” Overexpressing 14-3-3σ in mice skin reduces cell growth and hair density.
43 citations
,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
26 citations
,
April 1996 in “Journal of Investigative Dermatology” 13 citations
,
August 1985 in “The Journal of Dermatology” HKN-2 antibody targets specific skin and hair cells, showing keratin complexity.
30 citations
,
April 2017 in “European Journal of Cell Biology” CIP/KIP proteins help stop cell division and support hair growth.
10 citations
,
May 2018 in “Cell death discovery” HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.
198 citations
,
March 1999 in “Journal of Investigative Dermatology” Keratin 15 helps maintain tissue integrity and is reduced in activated keratinocytes.
April 2015 in “Journal of Investigative Dermatology” 13 citations
,
May 2017 in “Current Protocols in Stem Cell Biology” A method was developed to isolate and study hair follicle stem cells from mouse skin.
1 citations
,
January 2015 in “Journal of clinical case reports” KFSD causes scarring hair loss and skin roughness, mainly in males.
3 citations
,
May 2017 in “British journal of dermatology/British journal of dermatology, Supplement” Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
59 citations
,
March 1984 in “Journal of Investigative Dermatology” 25 citations
,
January 1988 in “Journal of Investigative Dermatology”
3 citations
,
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research reveals how early embryonic mouse skin develops from simple to complex structures, identifying various cell types and their roles in this process.
330 citations
,
December 2009 in “Cell stem cell” SKPs are similar to adult skin stem cells and could help in skin repair and hair growth.
32 citations
,
May 1999 in “Biochemical and Biophysical Research Communications” A new enzyme, BSSP, is found in high amounts in the hair follicles of nude mice.
September 2025 in “Digital Commons - RU (Rockefeller University)” Nfib in hair follicle stem cells boosts melanocyte stem cell growth and differentiation.
Human hair follicle cells can be turned into stem cells that may help clone hair for treating hair loss or burns.
6 citations
,
January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
January 2024 in “Animals” SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.
28 citations
,
January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
1 citations
,
October 2017 in “ecancermedicalscience” Breast cancer alters specific molecular structures in hair, which revert after cancer removal.
4 citations
,
March 2024 in “Journal of Investigative Dermatology” SPRY1 deficiency in skin cells causes stem cells to move to the skin surface, leading to increased pigmentation.
July 1995 in “Journal of Dermatological Science”
24 citations
,
November 2015 in “Scientific reports” Human hair has a new region with ordered filaments and the cuticle contains β-keratin sheets.