271 citations
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May 2019 in “Cells” The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.
266 citations
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November 2013 in “European Journal of Epidemiology” The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.
254 citations
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September 2014 in “Menopause” The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.
252 citations
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February 2018 in “npj Regenerative Medicine” Understanding different species' regeneration can improve mammalian healing.
244 citations
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September 2008 in “Annual Review of Genomics and Human Genetics” The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.
232 citations
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June 2012 in “Cold Spring Harbor Perspectives in Biology” Wnt signaling helps heal injuries and could lead to new treatments.
223 citations
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December 2010 in “The Journal of Sexual Medicine” Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.
222 citations
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October 2014 in “Annual Review of Pharmacology and Toxicology” Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.
220 citations
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March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
219 citations
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September 2009 in “European journal of epidemiology” The Rotterdam Study aims to understand various diseases in older adults.
212 citations
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September 2008 in “Journal of The American Academy of Dermatology” Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.
211 citations
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May 2013 in “Journal of Nutrition Health & Aging” MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.
208 citations
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July 2001 in “Journal of The American Academy of Dermatology” Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.
185 citations
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August 2020 in “Mayo Clinic Proceedings” Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.
182 citations
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November 2017 in “Molecular Aspects of Medicine” The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.
180 citations
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July 1973 in “The New England Journal of Medicine” Minoxidil effectively lowers blood pressure with few side effects.
177 citations
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December 2002 in “The Lancet” Fibrinogen/LDL apheresis may improve speech perception in sudden hearing loss, especially for those with high fibrinogen and LDL levels.
176 citations
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June 2017 in “Sexual Medicine Reviews” Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.
170 citations
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September 2019 in “Evidence-based Complementary and Alternative Medicine” Some medicinal plants can help heal wounds and may lead to new treatments.
166 citations
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October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
166 citations
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August 2010 in “Proceedings of the National Academy of Sciences of the United States of America” Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.
162 citations
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April 2016 in “The Lancet Diabetes & Endocrinology” Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.
162 citations
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January 2015 in “Trends in Endocrinology and Metabolism” Women with PCOS face higher risks of diabetes and heart disease, and these risks increase with obesity.
157 citations
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May 2021 in “Endocrine Reviews” Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.
155 citations
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March 2006 in “The American Journal of Medicine” Women with PCOS have heart-related issues not because of obesity, but due to insulin resistance and low adiponectin levels.
150 citations
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February 2013 in “Surgical Infections” Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.
143 citations
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April 2018 in “Electronic physician” More research is needed to confirm safflower's traditional medicinal uses.
142 citations
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March 2019 in “Frontiers in Cellular Neuroscience” The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
135 citations
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December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
128 citations
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July 2009 in “International Journal of Pharmaceutics” PEVs improve minoxidil skin penetration, increasing hair growth.