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Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.

A non-toxic formula using polycarboxylic acids strengthens and improves hair.

A new pair of mouse keratins, 65 kD and 48 kD, are found in specific skin areas and are linked to a unique skin differentiation type.

Understanding skin structure and function is key to managing skin diseases and improving quality of life.

α-type filaments in guinea pig hair follicles have unique structural features.

Keratin structure changes during keratinization, but the exact model remains uncertain.

Hair follicles form hard α-keratin filaments in four steps, showing structural differences.

The MPA-ISO cocrystal improved solubility and dissolution rate, while the others did not.

The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.

The study concludes that certain domains in Clostridium histolyticum enzymes are structurally unique, bind calcium to become more stable, and play distinct roles in breaking down collagen, with potential applications in medicine and drug delivery.

A specific type II hair keratin was identified and found in hair cortex and tongue cells.

Beauty standards cause widespread harm and need collective action to address.

Finasteride's molecular and crystal structures help develop new drug formulations.

Keratin proteins are crucial for hair growth and structure.

Sulfur mustard damages hair follicles and sebaceous glands in mice.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

The ovine Hoxc-13 gene is crucial for hair formation and may have other skin functions.

The B2 genes are crucial for hair growth in rats.

The hair's outermost surface has multiple layers of lipids and proteins.

Hair's structure and properties change with pH; acidic pH maintains strength and less swelling, while alkaline pH increases water content and swelling.

Hair's internal fibers are arranged in a pattern that doesn't let much water in, and treatments like oils and heat change how much water hair can absorb.

Modified pep7, named EPM peptide, effectively promotes hair growth at low concentrations and works well with minoxidil.

Chemical hair straightening improves smoothness and shine but may cause side effects, suggesting a need for safer methods.

Researchers developed a method to identify and analyze cyclosporin compounds and their structures effectively.

Canine skin has two main layers: the epidermis and dermis, with a supportive subcutis layer.

The patient's hair was thinner and had fewer lipids due to a genetic mutation.

The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.

Treatments improved hair surface and scale structure but didn't increase certain bonds in the hair cortex.