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Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

Certain compounds reduced hamster flank organ size by inhibiting 5α-reductase, like finasteride, without affecting androgen receptors.

Finasteride increases CD8+ T cells in BPH tissues.

Treatment with 5α-reductase inhibitors is linked to a delay in prostate cancer diagnosis and may affect survival rates.

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Gene variant linked to prostate cancer, hormone levels, and hair loss.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Researchers found a new gene variant linked to a rare bone disease, which doesn't always cause symptoms in carriers.

5α-reductase affects dopamine receptors linked to sensorimotor gating, which may help understand disorders like schizophrenia.

Sebaceous glands help study fatty acid transporters and binding proteins.

Grasp protein helps maintain skin health after UVB exposure.

The role of 5α-reductase-3 in prostate cancer is unclear and needs more research.

Errors found in identifying furosemide and finasteride polymorphs due to incomplete data.

A boy with a new NR5A1 gene mutation has a sex development disorder without affecting his adrenal glands.

A new method was developed to accurately measure enzyme activity related to prostate health.

The new assay can track and measure melanosome transfer between skin cells, confirming filopodia's role in this process.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

The new gel formula could improve the delivery of a hair loss treatment through the skin and might be an alternative to taking it by mouth.

The models can help find better inhibitors for conditions like baldness and prostate disorders.

Temporary hair loss can occur after 5-fluorouracil treatment for keloids.

5α-Reductase inhibitors don't cause depression.

PM-9 and finasteride effectively inhibit the enzyme that converts testosterone to DHT.

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

Lactobacillus paracasei HY7015 helps hair grow in mice.