Search

for
Search:

Did you mean Subcutaneous Tissue?

GlossarySubcutaneous Tissue

layer of fat and connective tissue beneath the skin

Subcutaneous tissue, also known as the hypodermis, is the layer of tissue directly beneath the skin (dermis). It consists primarily of fat and connective tissue, providing insulation, energy storage, and cushioning to protect underlying muscles and bones. This layer also contains larger blood vessels and nerves, playing a crucial role in thermoregulation and sensation.

Related Terms

Sort by

Research

30 / 1000+ results

Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome

research Evidence for Masculinization of Adipokine Gene Expression in Visceral and Subcutaneous Adipose Tissue of Obese Women With Polycystic Ovary Syndrome (PCOS)

58 citations , January 2013 in “The Journal of Clinical Endocrinology and Metabolism”

Obese women with PCOS show a male-like pattern in certain fat tissue gene expressions.

Expression of 11β-Hydroxysteroid Dehydrogenase Type 1 in Visceral and Subcutaneous Adipose Tissues of Patients with Polycystic Ovary Syndrome Is Associated with Adiposity

research Expression of 11β-hydroxysteroid dehydrogenase type 1 in visceral and subcutaneous adipose tissues of patients with polycystic ovary syndrome is associated with adiposity

18 citations , December 2010 in “The Journal of Steroid Biochemistry and Molecular Biology”

Increased HSD11B1 enzyme expression is linked to higher body fat and insulin resistance.

research Tracing the Change and Contribution of Subcutaneous Adipose to Skin Expansion Using a Luciferase-Transgenic Fat Transplantation Model

4 citations , May 2023 in “Plastic & Reconstructive Surgery”

Adipose tissue helps skin expand by increasing blood vessels and cell growth.

research Expression of transforming growth factor-beta (TGF-beta 1) and insulin-like growth factor II (IGF-II) messenger RNA in the developing subcutaneous tissue (SQ) of the fetal pig.

11 citations , January 1992 in “PubMed”

TGF-beta 1 and IGF-II mRNA have specific patterns in pig subcutaneous tissue, affecting fat and muscle development.

research Tissue engineering in burn scar reconstruction

41 citations , January 2015 in “Burns & Trauma”

Tissue engineering improves burn scar reconstruction by using skin substitutes and replacing damaged tissues.

research Does fat get you skinny?

1 citations , June 2015 in “Experimental Dermatology”

Fat may help skin health and repair, but more research is needed.

research Two-Stage Procedure to Correct Scalp and Facial Scars—Autologous Fat Grafting Before Hair Grafting

2 citations , September 2019 in “Dermatologic Surgery”

The two-step procedure of fat grafting followed by hair grafting improves scalp and facial scar correction.

research 559 Induction of tissue-specific premature stem cell aging promotes senescence-like phenotypes in remote multiple organs

November 2022 in “Journal of Investigative Dermatology”

Aging in one type of stem cell can cause aging-like changes in various organs.

research Cell-free fat extract improves embryo development and clinical outcomes in older women with previous in-vitro fertilization failure

1 citations , January 2025 in “Reproductive Biology and Endocrinology”

Cell-free fat extract may boost IVF success in older women with past failures.

research Increase in subcutaneous adipose tissue in the frontal scalp may be associated with androgenetic alopecia and metabolic syndrome.

June 2023 in “PubMed”

Thicker scalp fat may link hair loss with metabolic syndrome.

research Melanocyte progenitor cells reside in human subcutaneous adipose tissue

18 citations , August 2021 in “PLoS ONE”

Melanocyte progenitor cells are found in human fat tissue and can become mature melanocytes, which may help treat skin issues.

research Comparison of disease severity and ultrasonographic abdominal subcutaneous fatty tissue thickness in hirsute women

September 2018 in “Cumhuriyet medical journal”

Women with more body hair tend to have thicker belly fat and more metabolic health issues.

research Cause of Androgenic Alopecia

17 citations , October 2013 in “Plastic and reconstructive surgery. Global open”

Male pattern baldness may be caused by scalp pressure on hair follicles, which increases with age and leads to a cycle of hair loss. This process is not directly determined by genes.

New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats

research New Insight for Enhanced Topical Targeting of Caffeine for Effective Cellulite Treatment: In Vitro Characterization, Permeation Studies, and Histological Evaluation in Rats

7 citations , October 2024 in “AAPS PharmSciTech”

CA-SLN-Ngel significantly reduces cellulite more effectively than regular caffeine gel.

Characteristics of the Structural Components of Pilosebaceous Follicles in the Differential Diagnosis of Non-Cicatricial Alopecia

research Characteristics of the structural components of pilosebaceous follicles in the differential diagnosis of non-cicatricial alopecia

December 2025 in “Russian Journal of Skin and Venereal Diseases”

Hair follicles are thinner in alopecia patients, especially in alopecia areata.

research Çocukta obezite ile birlikte lipoödematöz skalp

September 2016 in “Ege tıp dergisi/Ege tıp dergisi :”

An 11-year-old obese girl was diagnosed with lipedematous scalp, a condition with swollen scalp tissue usually found in adult women.

research Wwox Deficiency Causes Downregulation of Prosurvival ERK Signaling and Abnormal Homeostatic Responses in Mouse Skin

6 citations , October 2020 in “Frontiers in cell and developmental biology”

WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.

Reprogramming Adult Dermis to a Neonatal State Through Epidermal Activation of Beta-Catenin

research Reprogramming adult dermis to a neonatal state through epidermal activation of β-catenin

128 citations , October 2011 in “Development”

Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.

Hand Rejuvenation: Multistage Protocol for Skin and Subcutaneous Tissues

research Hand rejuvenation

16 citations , December 2004 in “Aesthetic surgery journal”

The hand rejuvenation method makes hands look younger by improving skin and filling out tissues.

research Serum irisin level in patients with acne vulgaris

January 2024 in “International Journal of Dermatology Venereology and Leprosy Sciences”

Patients with acne vulgaris have lower serum irisin levels.

Sweat Glands Shrink Upward With Aging, Causing Dermal Layer Defects Leading to Loss of Skin Elasticity and Wrinkling - Establishment of 3D Imaging Method for Skin Appendages

research 250 Sweat glands shrink upward with aging, causing dermal layer defects that lead to loss of skin elasticity and wrinkling-establishment of 3D imaging method for skin appendages

September 2017 in “Journal of Investigative Dermatology”

Aging causes sweat glands to shrink and move upward, leading to less elastic skin and more wrinkles.

research Scanning Electron Microscopic Study on Collagen Fibrils in the Mink Dermis during the Hair Cycle and Growth

January 1994 in “Nihon Chikusan Gakkaiho”

Collagen fibrils in mink skin change structure during hair growth, becoming looser and thicker in the active phase.

Essential Fatty Acid Deficiency in a Patient with Vascular Ehlers-Danlos Syndrome

research Essential Fatty Acid Deficiency (EFAD) in a Patient with Vascular Ehlers Danlos Syndrome (EDS-4) (P12-053-19)

1 citations , June 2019 in “Current developments in nutrition”

A patient with Ehlers-Danlos Syndrome improved after treatment for fat malabsorption and essential fatty acid deficiency.

research Skin aging as a mechanical phenomenon: The main weak links

41 citations , May 2018 in “Nutrition and healthy aging”

Skin aging is largely due to differences in stiffness and elasticity between skin layers, leading to wrinkles.

research General theory of skin reinforcement

18 citations , August 2017 in “PLOS ONE”

Skin and its underlying fat layer act together to resist mechanical stress, and reinforcing this composite structure may help more with anti-aging than just strengthening the skin alone.

research Lipedema and lipedematous scalp: An overview

1 citations , July 2021 in “Journal of Skin and Sexually Transmitted Diseases”

Lipedema is a painful fat disorder in women that's hard to treat, often worsens with hormonal changes, and requires symptom-focused therapies.

research Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice

32 citations , January 2010 in “Journal of Dermatological Science”

Reduced EGFR signaling delays hair cycle and reduces fat growth, but hair development remains normal.

research Lipedematous alopecia: an uncommon clinicopathologic variant of nonscarring but permanent alopecia

30 citations , May 2008 in “International Journal of Dermatology”

Lipedematous alopecia causes permanent hair loss due to increased scalp fat.

Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

research Kojyl Cinnamate Ester Derivatives Increase Adiponectin Expression and Stimulate Adiponectin-Induced Hair Growth Factors in Human Dermal Papilla Cells

9 citations , April 2019 in “International Journal of Molecular Sciences”

Kojyl cinnamate ester derivatives can promote hair growth by increasing adiponectin production in fat tissues.

research Age-related changes in the dorsal skin histology in Mini and Wistar rats.

20 citations , April 2002 in “PubMed”

Mini rats have thinner skin, more fat, and different hair cycles than Wistar rats due to lower growth hormone levels.