February 2026 in “BMC Plastic and Reconstructive Surgery” Induced pluripotent stem cells could improve chronic wound healing but face safety and effectiveness challenges.
February 2026 in “American Journal of Clinical Dermatology” Radiotherapy can cause skin fibrosis, which is often overlooked and needs better treatment and evaluation.
January 2019 in “Advances in stem cells and their niches” Skin health and repair depend on the signals between skin stem cells and their surrounding cells.
October 1982 in “American Journal of Nursing” Wound healing is a complex process involving different cells and stages, leading to scar tissue formation and strength increase over time.
3 citations
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August 2011 in “InTech eBooks” The document concludes that skin grafts are essential for repairing tissue loss, with various types available and ongoing research into substitutes to improve outcomes and reduce donor site issues.
3 citations
,
February 2013 in “Journal of Medicinal Plants Research” Spirulina extract and C-phycocyanin may help heal wounds.
773 citations
,
August 2017 in “International Journal of Molecular Sciences” The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.
417 citations
,
September 2005 in “PLoS biology” Understanding gene expression in hair follicles can reveal insights into hair growth and disorders.
321 citations
,
March 2015 in “Nature” Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
254 citations
,
January 2012 in “Nature Reviews Molecular Cell Biology” Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
74 citations
,
January 2013 in “Expert Opinion on Biological Therapy” The conclusion is that hair growth can be improved by activating hair cycles, changing the surrounding environment, healing wounds to create new hair follicles, and using stem cell technology.
54 citations
,
November 2015 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
44 citations
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September 2019 in “The EMBO Journal” Lymphatic vessels are essential for hair follicle growth and skin regeneration.
30 citations
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April 2018 in “Experimental Dermatology” The article concludes that developing in vitro models for human hair structures is important for research and reducing animal testing, but there are challenges like obtaining suitable samples and the models' limitations.
30 citations
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December 2017 in “Medical Hypotheses” The model suggests that scalp tension could lead to hair loss, with factors like blood vessel hardening, enlarged oil glands, and poor microcirculation also playing a role. It also hints at a possible link between skull shape and baldness pattern.
22 citations
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November 2012 in “Journal of cosmetic dermatology” Stem cells can rejuvenate skin, restore hair, and aid in wound healing.
17 citations
,
June 2018 in “Frontiers in Physiology” ADM scaffolds help skin heal by promoting a healing-type immune response.
13 citations
,
January 2016 in “Burns & Trauma” Vacuum massage may improve skin elasticity and induce changes in skin cells, but evidence for treating burn scars is insufficient and more research is needed.
10 citations
,
January 2011 in “Journal of Cutaneous and Aesthetic Surgery” Surgical methods for hair loss are less common than hair transplants but still useful, especially for scarring hair loss.
3 citations
,
July 2020 in “International Journal of Molecular Sciences” SCDSFs from zebrafish embryos are beneficial for treating cancer, regenerating tissues, and improving conditions like psoriasis and alopecia.
2 citations
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January 2013 in “Hair therapy & transplantation” Hair transplants can be a treatment for scarring hair loss if there's good blood flow and no active disease.
March 2026 in “Frontiers in Immunology” Regulatory T cells help heal skin wounds by reducing inflammation and promoting tissue repair.
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
August 2017 in “Companion animal” Focal alopecia in dogs has many causes and requires various tests for accurate diagnosis and treatment.
January 2014 in “Journal of Pigmentary Disorders” Women's hair gets thinner and grayer as they age, with treatments available for hair loss and graying.
September 2013 in “Molecular Biology” The document suggests that activating autophagy might help with regeneration by removing old and damaged cells.
11 citations
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August 2018 in “Facial Plastic Surgery Clinics of North America” Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.
Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
688 citations
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June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.