research Proinflammatory cytokines regulate epidermal stem cells in wound epithelialization
Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.
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research C19and C215β/5αMetabolite Ratios in Subjects Treated with the 5α-Reductase Inhibitor Finasteride: Comparison of Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency*
Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
research An observational retrospective evaluation of 79 young men with long-term adverse effects after use of finasteride against androgenetic alopecia
Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.
research Identification of the causative dermatophyte of tinea capitis in children attending Mbarara Regional Referral Hospital in Uganda by PCR-ELISA and comparison with conventional mycological diagnostic methods
PCR-ELISA is better for identifying the fungus causing scalp infections in Ugandan children than traditional methods.
research Food Deprivation-induced Expression of Minoxidil Sulfotransferase in the Hypothalamus Uncovered by Microarray Analysis
Food deprivation increases MST enzyme in the brain, possibly affecting energy balance.
research Possible Therapeutic Effects of Ozone Mixture on Hypoxia in Tumor Development
Ozone therapy might improve cancer treatment and reduce its side effects.
research Fiber-Safe Extraction of Red Mordant Dyes from Hair Fibers
A new method extracts red dyes from wool without damaging it, although it slightly weakens the wool.
research Prostaglandin D2-Mediated DP2 and AKT Signal Regulate the Activation of Androgen Receptors in Human Dermal Papilla Cells
PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
research Fiber-Safe Extraction of Red Mordant Dyes from Hair Fibers
Researchers developed a less damaging way to extract red dyes from wool using EDTA and DMF, preserving the fiber's strength for further analysis.
research Inhibition of class I HDACs preserves hair follicle inductivity in postnatal dermal cells
Inhibiting class I HDACs helps maintain hair growth ability in skin cells.
research Keratin
Understanding how keratin structures in hair are arranged and interact is key for creating methods to extract and purify them.
research Non-apoptotic role for caspase-7 in hair follicles and the surrounding tissue
Caspase-7 has functions in skin and hair that are not related to cell death.
research Complémentarité et équilibre de l’apport alimentaire en protéines et en lipides
Vegetable protein lowers cholesterol and protein deficiency can cause health issues.
research How Does Altered Metabolism Lead to Seizure Control? Partially Filling the Knowledge Gap
Altered metabolism can help control seizures by changing brain signaling and energy use, suggesting new treatments for epilepsy.
research Susan Lee Lindquist (1949–2016)—pioneer in the study of cellular protein folding and disease
Susan Lee Lindquist was a pioneering biologist who made significant contributions to understanding protein folding and its role in disease.
research Reaction of Finasteride Intermediate with Benzeneseleninic Anhydride: An In-Depth Study
Impure benzeneseleninic anhydride samples cause lower finasteride intermediate yields.
research Biological and mechanical influence of three-dimensional microenvironment formed in microwell on multicellular spheroids composed of heterogeneous hair follicle stem cells
3D microenvironments in microwells improve hair follicle stem cell behavior and hair regeneration.
research In silico investigation of possible multi-target drugs against Glutamate S-transferase and prolyl tRNA synthetase in Onchocerca volvulus
Bedaquiline, Telmisartan, Diosmin, Azelastine, and Adapalene may be effective treatments for onchocerciasis.
research Anti-inflammatory loading of cinnamaldehyde on artificial bone scaffolds against the process of bone regeneration
Cinnamaldehyde helps bone healing initially but may slow healing later unless combined with DHT treatment.
research ‘’Brown adipose tissue in the form of innovative approach for polycystic ovary syndrome treatment-still long time to reach clinical arena: a narrative review’’
More research is needed before using brown fat to treat polycystic ovary syndrome.
research Metformin effects on Polycystic Ovarian Syndrome
Metformin may help regulate periods and cause modest weight loss in PCOS patients, but more research is needed.
research Greasy hair against obesity
Increasing sebum production might help reduce fat and improve metabolism.
research Dermoscopic evaluation of tinea capitis: A case report
A 12-year-old boy's hair fully regrew after 8 weeks of treatment for tinea capitis, and dermoscopy was useful for diagnosis and monitoring.
research Injection/Application of Micrografts
Micrografts are useful for healing wounds, regenerating bone and periodontal tissues, and improving hair transplantation outcomes.
research Hallmark evidence of lipopolysaccharide (LPS) tolerance in obese women with polycystic ovary syndrome (PCOS) - LPS-induced NFkB suppression in mononuclear cells (MNC) is linked to hyperandrogenism in PCOS
High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.
research Neurosteroids on the Epilepsy Chessboard—Keeping Seizures in Check
Ketogenic diet, neurosteroids, and HMGB1-TLR4 signaling pathway are potential targets for new epilepsy treatments.
research Hirsutism
Excessive hair growth in women, often from high androgen levels, is usually caused by PCOS, and can be treated with hair removal, medication, and possibly weight loss.
research Abstracts Pt.30
Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.
research Treatment of localized scleroderma and lichen sclerosus with etretinate
Etretinate has only moderate effects on localized scleroderma and lichen sclerosus.
research Topical Application of Thymidine Dinucleotide to Newborn Mice Reduces and Delays Development of UV-Induced Melanomas
Putting thymidine dinucleotide on newborn mice's skin can delay and reduce skin cancer.