34 citations
,
October 1982 in “Journal of applied polymer science” Moisture content significantly affects how human hair breaks.
42 citations
,
January 2002 in “Skin Pharmacology and Physiology” Reconstructed skin models are useful for studying how skin processes certain chemicals.
30 citations
,
October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
Understanding hair surface properties is key for effective hair care products.
August 2024 in “Latin American Journal of Development” 5α-reductase enzymes are crucial in certain disorders, and while treatment advances exist, more research on SRD5A3 is needed.
12 citations
,
September 1990 in “The Anatomical Record” Human anagen hair follicles have unique carbohydrate patterns during keratinization.
23 citations
,
November 1964 in “Journal of Dairy Science” High molybdenum and sulfate sulfur levels can cause health issues in cattle, but adding copper helps.
30 citations
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November 2012 in “Proceedings of the Royal Society B Biological Sciences” Hard α-keratins stay stiff in water because the surrounding matrix keeps them dehydrated and strong.
April 2014 in “The FASEB Journal” Geranium Sibiricum L extract may promote hair growth by increasing growth factors and decreasing inhibitory factors under stress.
November 2024 in “Journal of Investigative Dermatology” Scalp hair follicle cells help protect and heal skin in certain skin conditions.
9 citations
,
November 2004 in “Bioorganic & Medicinal Chemistry Letters” New compounds were made that effectively block enzymes related to prostate issues and hair loss.
May 2023 in “Pharmaceuticals” Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.
7 citations
,
February 2012 in “British Journal of Dermatology” TH antibodies in vitiligo and AA patients recognize the same protein parts.
6 citations
,
January 1988 in “Japanese Journal of Medicine” Hair glycation levels can indicate long-term blood sugar control.
7 citations
,
March 2003 in “Journal de Physique IV (Proceedings)” Calcium soaps are present in human hair and can be removed with acid.
115 citations
,
March 2001 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Key enzymes control androgen levels, affecting hormone activity and potential treatments.
13 citations
,
April 1997 in “Biochemical and Biophysical Research Communications” Insulin-dependent diabetes alters hair's molecular structure, making it useful for studying diabetes effects.
May 2021 in “The FASEB Journal” The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.
48 citations
,
November 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Genetic variations in hair keratin proteins exist but don't significantly affect hair structure.
4 citations
,
January 2015 in “Journal of microbial & biochemical technology” Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
January 1995 in “Journal of the Society of Cosmetic Chemists” Transglutaminase does not modify human hair.
8 citations
,
November 1976 in “Journal of Investigative Dermatology” May 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” Targeting specific metabolic and ionic pathways may improve alopecia areata treatment.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Targeting impaired Nrf2 signaling might help treat hidradenitis suppurativa early on.
13 citations
,
October 1960 in “Experimental Biology and Medicine” Selenium-75 stays in dog hair for up to 316 days.
April 2026 in “Applied Sciences” Succinic acid helps improve skin conditions like acne and rosacea.
20 citations
,
June 2007 in “Recent Patents on Endocrine, Metabolic & Immune Drug Discovery” Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
35 citations
,
February 2003 in “Biochimica et Biophysica Acta (BBA) - General Subjects” Lead can help reveal and organize lipids in human hair.
December 2012 in “SWU eJournals System (Srinakharinwirot University)” Chemical hair removal can cause skin irritation and other issues, but natural alternatives are being explored.
1 citations
,
December 2024 in “Methods in molecular biology” Hair proteins are complex and provide valuable genetic and biological information.