431 citations
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October 2008 in “Current Medicinal Chemistry” Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.
87 citations
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March 2014 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
47 citations
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September 2016 in “Reviews in endocrine and metabolic disorders” The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
33 citations
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April 1990 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, with better results in women.
14 citations
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August 2020 in “Dermatologic Therapy” Low-dose oral minoxidil is a safe treatment for hair loss, with the main side effect being excessive hair growth. Other side effects like foot swelling, low blood pressure when standing, and heart rate changes are rare.
12 citations
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July 2020 in “Dermatologic Therapy” Minoxidil, applied on the skin or taken orally, can improve hair growth in kids, but more research is needed due to possible side effects.
5 citations
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December 1991 in “Annals of the New York Academy of Sciences” Minoxidil boosts hair growth by undergoing a process in hair follicles and certain skin cells, and by increasing the production of compounds essential for hair growth and maintenance.
3 citations
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April 2010 in “Journal of Receptors and Signal Transduction” Minoxidil, a common alopecia medication, might cause eye changes due to its properties and lack of tissue selectivity.
3 citations
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January 2009 in “Eclética Química” A simple and quick method was found to measure minoxidil in drugs accurately.
1 citations
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January 2019 in “Elsevier eBooks” Neuroactive steroids may affect the risk and treatment of alcohol use disorders.
March 2026 in “Saudi Journal of Pathology and Microbiology” Personalized genomic interventions can effectively manage chronic hair loss.
January 2026 in “Frontiers in Pharmacology” Minoxidil can treat hair loss with topical, oral, and sublingual options, offering personalized choices.
Low-dose oral minoxidil is generally safe for treating hair loss, with mostly mild side effects.
January 2018 in “Elsevier eBooks” Minoxidil helps lower severe blood pressure and promotes hair growth but can have serious side effects and must be used continuously.
September 2014 in “Springer eBooks” Men and women experience skin aging differently due to changes in sex hormone levels with age.
March 2014 in “Human Physiology” DHEA improved brain function and behavior in old monkeys and had additional health benefits.
January 2019 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” Non-ablative radio frequency can potentially increase hair count in men with androgenetic alopecia, but some may be bothered by the smell during treatment.
403 citations
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November 2005 in “Journal of Endocrinology” Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
117 citations
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August 2019 in “Drug Design Development and Therapy” Minoxidil effectively treats hair loss, but use cautiously and monitor side effects.
53 citations
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February 2020 in “Expert Opinion on Pharmacotherapy” Finasteride and minoxidil work best together for hair loss.
28 citations
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January 2013 in “Journal of Thyroid Research” Thyroid hormone may speed up wound healing and hair growth, but more research is needed to understand its role in skin repair and use as a treatment.
17 citations
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August 2015 in “Expert Opinion on Pharmacotherapy” The document concludes that oral finasteride and topical minoxidil are effective for genetic hair loss, while other treatments for different types of hair loss show promise but need more research.
January 2004 in “Online Publication Service of Würzburg University (Würzburg University)” Women with PCOS have higher 5alpha-reductase activity, affecting steroid levels.
80 citations
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April 2011 in “Plant physiology” White lupin uses specific genes to grow root hairs and access phosphorus when it's scarce.
397 citations
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February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
25 citations
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November 2018 in “Cell reports” The study concluded that specific proteins are necessary to maintain the structure that holds epithelial cells tightly together.
22 citations
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January 2008 in “Physiological Research” Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
118 citations
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October 2013 in “Trends in Genetics” The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.
80 citations
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August 1991 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Methotrexate reduced the need for steroids in asthma patients without worsening their condition.
28 citations
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February 2016 in “F1000Research” Understanding glycans and enzymes that alter them is key to controlling hair growth.