research Stimulation of melanogenesis by Carthamus tinctorius floret extract in B16F10 murine melanoma cells
Safflower extract increases melanin production in certain skin cells without harming them.
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810-840 / 1000+ resultsresearch Low-Dose Dimethyl Sulfoxide (DMSO) Suppresses Androgen Receptor (AR) and Its Splice Variant AR-V7 in Castration-Resistant Prostate Cancer (CRPC) Cells
Low-dose DMSO may help treat castration-resistant prostate cancer by reducing key cancer cell receptors.
research The Quantification of Terminal Hair by Digital Microscopy: Advancements Towards a More Objective Diagnosis of Hirsutism
Digital microscopy can help diagnose hirsutism by measuring hair growth.
research Treatment of hirsutism with the pure antiandrogen flutamide
Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.
research 5-Bromo-2′-deoxyuridine induced effluvium via p53-mediated CD326-positive keratinocyte apoptosis in C57BL/6 mice
A chemical called 5-Bromo-2′-deoxyuridine caused rapid hair loss in mice by killing certain skin cells through a specific cell death pathway.
research Cyproterone Acetate Quantification in Human Plasma by High-performance Liquid Chromatography Coupled to Atmospheric Pressure Photoionization Tandem Mass Spectrometry
The method accurately measures cyproterone acetate in plasma, showing no significant difference between two formulations.
research Maladaptive Hypothyroidism, or The Famine Response, After Bariatric Surgery: TSH not the Gold Standard For Detection
TSH is not reliable for detecting hypothyroidism after bariatric surgery; FT3/rT3 ratio is better.
research Formulation and evaluation of self-nanoemulsifying drug delivery system for improved oral delivery of exemestane hydrochloride
The new drug delivery system improves exemestane's absorption and effectiveness.
research Comedonal and Cystic Fibrofolliculomas in Birt-Hogg-Dube Syndrome
Early detection of specific skin lesions can help identify Birt-Hogg-Dube syndrome and prevent serious complications.
research Organ culture of human hair follicles in serum-free medium
Hair follicles can grow and increase DNA synthesis in a serum-free environment, and minoxidil sulphate boosts this process.
![Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)](/images/research/d743d32f-3115-48ff-9697-2f2d56130701/small/14175.jpg)
research Verification of the Major Metabolic Oxidation Path for the Naphthoyl Group in Chemoattractant Receptor-Homologous Molecule Expressed on Th2 Cells (CRTh2) Antagonist 2-(2-(1-Naphthoyl)-8-fluoro-3,4-dihydro-1H-pyrido[4,3-b]indol-5(2H)-yl)acetic Acid (Setipiprant/ACT-129968)
The document confirms the structures of major metabolites of the CRTh2 antagonist Setipiprant and identifies minor metabolites.
research Gloriosa superba poisoning mimicking an acute infection- a case report
Gloriosa superba poisoning can mimic severe tropical infections and cause rapid hair loss.
research 496 Understanding the mechanism of action of secukinumab using lesional hidradenitis suppurativa skin organ culture
Secukinumab reduces immune activity in hidradenitis suppurativa skin.
research Extraction and Analysis of Cortisol from Human and Monkey Hair
Hair cortisol analysis effectively measures long-term stress.
research In vitro bioassays for androgens and their diagnostic applications
In vitro bioassays are better than traditional methods for measuring androgen activity but aren't ready for routine use yet.
research Metabolism of subtoxic levels of selenium in animals and humans.
The safe daily selenium intake is up to 819 micrograms.
research Efficacy and safety of deuruxolitinib, an oral selective Janus kinase 1/2 inhibitor, in adults with alopecia areata: Results from the THRIVE-AA2 Phase 3, randomized, double-blind, controlled trial
Deuruxolitinib effectively regrows hair in adults with alopecia areata and is well tolerated.
research The determination of endogenous steroids in hair and fur: A systematic review of methodologies
research Comparative analysis of 3D and 2D cell-culturing methods in hair follicle spheroid morphogenesis and drug responsiveness
3D cultures respond better to minoxidil, while 2D cultures respond better to DHT.
research The Photoprotective Effect of S-Methylmethionine Sulfonium in Skin
S-Methylmethionine sulfonium can protect skin from UVB damage.
research Optimization of Ultrasonic-Assisted Extraction of Total Saponins fromEclipta prostrastaL. Using Response Surface Methodology
The best way to extract saponins from Eclipta prostrasta is using 70% ethanol, at 70°C for 3 hours with a 14:1 liquid to solid ratio.
research Natural Product-InspiredBis(trifluoromethyl) PhenylHydroxycinnamate Derivatives as Promising Nonsteroidal Inhibitorsof Human Steroid 5α-Reductase Type-1: Synthesis, InVitro, and In Silico Studies
Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.
research Evaluating Carthamus Oxyacantha For 5α-Reductase Inhibition: Therapeutic Perspectives In BPH
Carthamus oxyacantha may help treat BPH by inhibiting 5α-reductase.
research Design of a gelatin microparticle-containing self-microemulsifying formulation for enhanced oral bioavailability of dutasteride
The new formulation improves dutasteride's absorption when taken orally.
research Solubility of Foreign Molecules in Stratum Corneum Brick and Mortar Structure
Solubility in skin changes with hydration, affecting chemical absorption.
research The Clinical Evaluation of Serum WS Biotin, a Novel Encapsulated Form of D‐Biotin With Improved Water Solubility, for Anti‐Hair Shedding Applications. A Prospective Single‐Arm, Nonrandomized, Pretest−Posttest Study
Serum WS Biotin significantly reduces hair shedding and improves hair thickness.
research Ziehl-Neelsen's stain for skin sections to show wool and hair follicles
Ziehl-Neelsen's stain helps identify different parts of hair in sheep and goats.
research Validation of hair estradiol immuno-assays across the menstrual cycle in emerging adults
Hair samples can reliably show average long-term hormone levels in young women.
research 554 Repurposing a clinical antimalarial for the therapeutic induction of lethal ER stress targeting BRAF-kinase inhibitor-resistant malignant melanoma
Mefloquine, an antimalarial drug, is effective in killing melanoma cells resistant to other treatments by causing lethal stress in the cells.