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Synthesis and Structure–Activity Investigation of Iodinated Arylhydantoins and Arylthiohydantoins for Development as Androgen Receptor Radioligands

research Synthesis and structure–activity investigation of iodinated arylhydantoins and arylthiohydantoins for development as androgen receptor radioligands

6 citations , November 2004 in “Bioorganic & Medicinal Chemistry Letters”

Scientists created iodinated arylhydantoins and arylthiohydantoins that could potentially be used for imaging prostate cancer. Some versions with specific side-chains showed high potential for this use.

research A rapid method for obtaining finasteride, a 5α-reductase inhibitor, from commercial tablets

14 citations , April 2002 in “Brain Research Protocols”

Quickly get finasteride from tablets using easy methods.

Transcranial Focused Ultrasound-Mediated Unbinding of Phenytoin for Suppression of Chronic Temporal Lobe Epilepsy in a Rodent Model

research Transcranial focused ultrasound-mediated unbinding of phenytoin from plasma proteins for suppression of chronic temporal lobe epilepsy in a rodent model

March 2023 in “Scientific Reports”

Using focused ultrasound on the brain can help epilepsy medicine work better in rats.

research Development of radioiodinated nonsteroidal androgen receptor ligands for spect imaging of prostate cancer

1 citations , May 2001 in “Journal of Labelled Compounds and Radiopharmaceuticals”

Scientists at the University of Michigan Medical School successfully created a special compound that can be used to improve imaging of prostate cancer.

research RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF FINASTERIDE AND TAMSULOSIN IN TABLET FORMULATIONS

January 2015 in “INDONESIAN JOURNAL OF PHARMACY”

A reliable method was developed to measure Tamsulosin and Finasteride in tablets accurately.

research Identification of xenobiotics interfering with 5 α -reductase (SRD5A2) activity

February 2026 in “Toxicology Letters”

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

research Structural changes in hair follicles and sebaceous glands of hairless mice following exposure to sulfur mustard

14 citations , March 2014 in “Experimental and Molecular Pathology”

Sulfur mustard damages hair follicles and sebaceous glands in mice.

research SULFUR TREATMENT FOR SCABIOSIS IN LOCAL PUPPY

July 2023 in “Jurnal Ilmu Kesehatan Hewan”

Sulfur-based treatments combined with simparica effectively treat scabies in puppies.

research Synthesis, Characterization and Evaluation of 5α, 6β-Dihalo Androsterone Derivatives as 5α-Reductase Inhibitors

May 2022 in “Current Enzyme Inhibition”

Compound 7b is a promising candidate for treating benign prostatic hyperplasia and prostate cancer.

research Enhanced hair follicle accumulation and androgenetic alopecia treatment of finasteride by topical nanoparticles hydrogel system

December 2024 in “Chinese Chemical Letters”

A new topical finasteride gel using nanoparticles shows promise for safe and effective hair regrowth.

research Crystallization Engineering in Aza-Steroid: Application in the Development of Finasteride

October 2012 in “Organic Process Research & Development”

A new method was developed to purify finasteride for better medical use.

research Minoxidil Multi-Component Crystals with Aromatic Carboxylic Acids: Theoretical Calculation and Structural Analysis

1 citations , April 2022 in “Crystal Growth & Design”

research Teriflunomide in multiple sclerosis: an update

20 citations , December 2016 in “Neurodegenerative disease management”

Teriflunomide effectively reduces relapses and disability in MS and has a manageable safety profile.

research Novel fabrication and development of multifunctional Zn/Fu@Cs nanofibers material for wound care and operate room infection control

5 citations , October 2022 in “Materials Research Express”

The nanofibers effectively fight bacteria and help wounds heal faster.

research Effect of selenium sulfide suspension on hair roots.

20 citations , August 1960 in “PubMed”

Selenium sulfide may affect hair root health.

research Pharmacodynamics and pharmacokinetics of P-3074, a new finasteride topical solution, administered at four different doses

January 2014

P-3074 effectively blocks scalp DHT better than oral finasteride.

research Crystal Structure of Minoxidil

5 citations , January 2004 in “Analytical Sciences X-ray Structure Analysis Online”

Minoxidil's crystal structure shows two different molecule shapes and nitrogen states.

research Estranys matins de febrer: Pauline Fondevila

January 2006 in “Benzina: Revista d'excepcions culturals”

Trienones are more effective at inhibiting the enzyme linked to hair loss than dienones.

research The Evidence for Microbes in the Small Intestine as the Mechanism for Post-Finasteride Syndrome: Self-Reported Case Study

April 2026 in “Open MIND”

Microbes in the small intestine may cause Post-Finasteride Syndrome symptoms.

research New Synthesis of Methyl 3β-Hydroxy-5-androstene-17β-carboxylate

January 2002 in “Chinese Journal of Pharmaceuticals”

A new method was developed to make a compound used in finasteride and epristeride with a 69% yield.

research 3,3-Diphenylpentane skeleton as a steroid skeleton substitute: Novel inhibitors of human 5α-reductase 1

13 citations , August 2007 in “Bioorganic & medicinal chemistry letters”

A new compound effectively inhibits human 5α-reductase 1.

research Process Development and Crystallization in Oiling-Out System of a Novel Topical Antiandrogen

9 citations , January 2017 in “Organic Process Research & Development”

In 2017, a new method was created to efficiently produce a topical antiandrogen, a compound used to treat excess sebum and acne, with a high yield and purity.