106 citations
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April 2010 in “ACS Nano” C60 fullerenes can alter protein function and may help develop new disease inhibitors.
54 citations
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February 1993 in “Endocrine reviews” Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.
22 citations
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January 2008 in “Physiological Research” Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
9 citations
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May 2012 in “PLOS ONE” ILK is essential for skin development, pigmentation, and healing.
25 citations
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July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
6 citations
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February 2018 in “PubMed” Minoxidil helps hair growth by promoting stem cell differentiation through increased ATP synthase activity.
7 citations
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August 2023 in “Life” Extracellular vesicles could help tailor drug treatments, but more research is needed.
January 2025 in “Case Reports in Gastrointestinal Medicine” Topical minoxidil can cause severe liver failure.
7 citations
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January 2023 in “Journal of Hematology & Oncology” Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.
12 citations
,
January 2019 in “Journal of Endocrinology” Baicalin may help reduce excessive male hormone levels in PCOS.
March 2026 in “Journal of Personalized Medicine” Genetic differences affect breast cancer treatment success with tamoxifen in South African patients.
November 2023 in “Bioorganic Chemistry” Drugs targeting the Androgen Receptor are effective for treating prostate cancer and other androgen-related conditions.
1 citations
,
March 2011 in “Informa Healthcare eBooks” Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.
July 2017 in “Contemporary Endocrinology” The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.
43 citations
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August 2014 in “Dermatologic Therapy” Minoxidil response testing helps treat hair loss effectively and safely.
33 citations
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April 1990 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, with better results in women.
21 citations
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March 2021 Oral minoxidil effectively treats hair loss, with women needing lower doses (0.25 to 2.5 mg daily) and men needing higher doses (1.25 to 5 mg daily).
14 citations
,
August 2020 in “Dermatologic Therapy” Low-dose oral minoxidil is a safe treatment for hair loss, with the main side effect being excessive hair growth. Other side effects like foot swelling, low blood pressure when standing, and heart rate changes are rare.
January 2019 in “Acta dermatovenerologica Alpina, Pannonica et Adriatica (Tiskana izd.)” Non-ablative radio frequency can potentially increase hair count in men with androgenetic alopecia, but some may be bothered by the smell during treatment.
87 citations
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March 2014 in “Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids” Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.
48 citations
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January 2000 in “Hormone Research in Paediatrics” Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.
47 citations
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November 2012 in “Expert Opinion on Therapeutic Patents” The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
13 citations
,
August 1997 in “Steroids” Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.
12 citations
,
July 2020 in “Dermatologic Therapy” Minoxidil, applied on the skin or taken orally, can improve hair growth in kids, but more research is needed due to possible side effects.
5 citations
,
August 2021 in “Journal of The European Academy of Dermatology and Venereology” Sublingual minoxidil safely promotes hair growth.
5 citations
,
December 1991 in “Annals of the New York Academy of Sciences” Minoxidil boosts hair growth by undergoing a process in hair follicles and certain skin cells, and by increasing the production of compounds essential for hair growth and maintenance.
4 citations
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May 2020 in “Medicine in Drug Discovery” The study developed a method to detect minoxidil and its sulfate form, found that minoxidil sulfate is temperature-sensitive, and identified a way to potentially increase its stability for hair loss treatment.
5 citations
,
January 2018 in “Skin appendage disorders” Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.
October 2023 in “JOJ dermatology & cosmetics” Thiocyanate helps hair growth and can be supplemented in diet or applied topically.
16 citations
,
June 2021 in “Journal of Dermatological Treatment” Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.