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Genetic testing is crucial before giving azathioprine to avoid severe side effects.

A genetic defect causes males in some Mediterranean populations to be born with ambiguous genitalia and develop male traits at puberty.

Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Self-amplifying RNA could be a better option for protein replacement therapy with lower doses and lasting effects, but delivering it into cells is still challenging.

Minoxidil helps hair growth by activating enzymes in hair follicles.

Targeting mitophagy may help treat alopecia areata by reducing inflammasome activation.

Mutations in the RBPJ gene cause Adams-Oliver Syndrome.

Genetic variants can affect valproic acid's effectiveness, side effects, and levels in epilepsy treatment.

Increasing m6A levels can improve skin cell growth and wound healing.

A special receptor in sensory nerve endings helps control how they respond to stretching.

A new engineered treatment shows promise in curing heart fibrosis.

Genetic variations affect dutasteride treatment response for male pattern hair loss.

People with the same genetic mutation for Woodhouse-Sakati syndrome can have different symptoms.

Adrenomedullin 2 stops cell growth and causes cell death in human hair follicles.

Two new gene clusters important for hair formation were found on human chromosome 11.

Tissue-specific variation in mutant load complicates genetic counseling and prenatal diagnosis.

UTX is important for skin health and its loss can lead to skin issues, especially in females.

Dapagliflozin improved blood sugar control in a man with Werner syndrome without side effects.

CRISPR/Cas9 and prime editing can potentially fix skin disorder genes safely and effectively.

The Trichodysplasia spinulosa virus protein can cause abnormal hair growth in mice.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

The scraggly mutation causes hair loss and skin defects in mice.

The enzymes Aldh1a2 and Aldh1a3 are involved in making retinoic acid in hair follicles and have different roles in hair growth.

A gene mutation in mice causes skin defects and early death.

Cortisol increases a specific protein in bone cells, which may help explain its negative effects on bone.

A genetic variant in the KRT25 gene causes tightly curled hair.