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A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

The research gives new understanding on how human steroid 5α-reductases work and how drugs like finasteride inhibit them, which could help in creating new drugs.

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.

ATP-sensitive K+ channel subunits, particularly Sur2A, play a significant role in various cancers.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Different sPLA2 enzymes have unique roles in phospholipid metabolism and biological processes.

A(1-7) treatment reduces symptoms of lupus in mice.

TMPRSS2 affects COVID-19 severity and treatment options.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

QSOX enzymes help form protein bonds in cells, especially in tissues with high secretory activity.

Two specific genes are more active during hair growth in mice.

A genetic mutation in a specific gene causes a salt-wasting condition in a Pakistani girl and her family.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

SRD5A1 is crucial in advanced prostate cancer, and blocking both SRD5A1 and SRD5A2 is more effective than targeting SRD5A2 alone.

Targeting 5α-reductase type 1 may help manage Tourette-like symptoms.

Sirtuin 1 could be a potential drug target for treating hypertrophic scars.

Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.

A new gene mutation causes insulin resistance in a girl and her mother.

Blocking CYP17A1 enzyme may help improve certain brain function issues related to dopamine.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Scientists found a new gene in a bacterium that can modify an immunosuppressant drug, potentially helping to treat hair loss.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

New probes were created to effectively measure specific enzymes involved in fat metabolism, which could help develop new drugs.

Skin tumor cells in patients with tuberous sclerosis have higher levels of a protein called cathepsin B.

Certain genetic variants reduce enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

TMPRSS2 is crucial for COVID-19 infection and is a potential target for treatment.