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A specific gene variant is linked to severe insulin resistance and hormone imbalance in a teenage girl.

A(1-7) treatment reduces symptoms of lupus in mice.

CSLD1 suppresses rice root hair growth with NH4+ and regulates AMT1;2 expression.

TMPRSS2 is crucial for COVID-19 infection and is a potential target for treatment.

Ubiquitination of the insulin receptor regulates collagen secretion in human skin.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

A new mutation in the STING protein causes a disease with lupus-like symptoms and responds well to a specific inhibitor treatment.

Minoxidil boosts hair growth in genetically modified mice.

PLAU and SerpinB2 affect cell death differently in various forms of leprosy and could be targets for new treatments.

Scientists found a new gene in a bacterium that can modify an immunosuppressant drug, potentially helping to treat hair loss.

Certain genetic markers can indicate higher or lower risk for systemic lupus erythematosus.

The study found two new mutations in a Chinese patient with severe biotinidase deficiency.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

OsUEV1B protein is essential for controlling phosphate levels in rice.

Type 3 5α-reductase is more common and finasteride and dutasteride strongly inhibit it.

SQSTM1 is linked to increased risk of alopecia areata.

SIRT7 protein is crucial for starting hair growth in mice.

New genes and pathways are important for testosterone production and male sexual development.

Targeting Sirt1 can reduce androgen levels and slow glioblastoma growth.

Sphingosine 1-phosphate affects inflammation and gene expression in different aorta cells.

MK-0773 is a moderate inhibitor of the SRD5A2 enzyme.

LY191704 is a compound that effectively blocks a specific enzyme involved in hormone conversion and could help treat enlarged prostate and hair loss.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Certain genetic variants impair enzyme activity, contributing to non-classic congenital adrenal hyperplasia.

Matriptase-2 helps control iron levels by suppressing hepcidin, and its deficiency can cause iron-deficiency anemia.

5α-reductase 2 is crucial for stress response in male rats.

The boy's severe skin disorder is caused by two new mutations in his TGM1 gene.