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CNGA3, GLUD1, and SIRT1 are promising targets for treating aging and glioblastoma.

A child with ectodermal dysplasia-syndactyly syndrome has a new mutation in the NECTIN4 gene.

Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.

PSAT1 is key for hair growth and stem cell function in cashmere goats.

An elderly Chinese man lost all his hair after taking a new heart medication.

Rat skin can convert minoxidil into its active form, aiding hair growth.

A rare genetic mutation causes Woodhouse-Sakati syndrome symptoms.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Astrotactin2 affects hair follicle orientation and skin cell polarity.

ETS2 drives cancer progression in squamous cell carcinoma and is linked to poor patient outcomes.

IL-19 and IL-24 help cells respond to DNA damage and could be targeted for cancer and age-related disease treatments.

WNT10A gene mutations cause short anagen hair syndrome.

Certain amino acids in 5AR1 and 5AR2 are crucial for binding and resistance to Finasteride.

A new mutation in the KRT86 gene was found to cause the hair disorder monilethrix in a Han family.

Most Recessive Dystrophic Epidermolysis Bullosa patients with a specific mutation likely have Sephardic ancestry from about 500 years ago.

Upadacitinib can cause hypersensitivity that worsens ulcerative colitis symptoms.

The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.

The p.P25L mutation in the KRT5 gene causes a rare skin condition that worsens over time and may lead to hair loss starting in young adulthood.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

Environmental factors affect reproductive traits by altering the SRD5A1 gene.

Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

Sdr16c5 and Sdr16c6 genes regulate a key point in lipid production that affects eye and skin gland function.

QSOX enzymes help form protein bonds in cells, especially in tissues with high secretory activity.

Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.

Both SMS1 and SMS2 are crucial for normal hair growth and cycle in mice.

Anti-DFS70 antibodies can help identify nonsystemic autoimmune conditions in SLE patients.

Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.

LSD1 and HSP90 help heal skin wounds by changing hair follicle stem cells' metabolism.