39 citations
,
January 2018 in “British journal of dermatology/British journal of dermatology, Supplement” Acne and hidradenitis suppurativa have different causes and risk factors, but both are driven by inflammation and may benefit from treatments targeting interleukin-1.
30 citations
,
June 2015 in “Dermatologic Surgery” Ultrasound shows 80% of Hidradenitis Suppurativa patients have abnormal hair tracts that may worsen the condition.
29 citations
,
January 2016 in “Experimental Dermatology” Mechanical stress may cause lesions in Hidradenitis suppurativa.
28 citations
,
August 2020 in “F1000Research” Better understanding and new treatments for hidradenitis suppurativa are emerging, but more research is needed.
27 citations
,
May 2019 in “American Journal of Clinical Dermatology” Antiandrogen therapy for hidradenitis suppurativa lacks strong evidence and needs more research.
25 citations
,
December 2018 in “Human Molecular Genetics” The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
24 citations
,
January 2017 in “Dermatology online journal” Hormonal therapies might help treat hidradenitis suppurativa, but treatment is complex and personalized.
24 citations
,
June 2008 in “Journal of Cutaneous Pathology” The exact cause of hidradenitis suppurativa is still unknown.
22 citations
,
August 2021 in “Frontiers in medicine” Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
22 citations
,
September 2020 in “Journal of the American Academy of Dermatology” Apremilast may be a promising long-term treatment for hidradenitis suppurativa.
19 citations
,
August 2018 in “JAMA dermatology” Mesenchymal stem cells in people with Hidradenitis Suppurativa are more inflammatory, possibly contributing to the disease.
19 citations
,
July 2017 in “Pediatric Dermatology” Finasteride improves hidradenitis suppurativa in children with no adverse effects.
15 citations
,
December 2021 in “Pharmaceutics” The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.
14 citations
,
January 2015 in “Acta dermato-venereologica” Acitretin significantly reduced inflammatory attacks in a woman with Naevus Comedonicus Syndrome but caused side effects.
11 citations
,
September 2000 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” The document concludes that awareness and understanding of hidradenitis suppurativa are increasing, but effective treatments are still needed.
10 citations
,
May 2024 in “Lasers in Surgery and Medicine” Laser hair removal effectively reduces hidradenitis suppurativa symptoms with few side effects.
9 citations
,
June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
9 citations
,
July 2017 in “Case Reports in Dermatology” Combination therapy helped patient with advanced Hidradenitis Suppurativa achieve remission.
8 citations
,
July 2024 in “Children” Biologics and targeted therapies could improve treatment for children with certain chronic skin conditions.
8 citations
,
October 2021 in “European Journal of Dermatology” Wounds heal faster in the anogenital/inguinal area than in the axillary area after surgery for hidradenitis suppurativa.
8 citations
,
June 2016 in “PubMed” Finasteride is effective and safe for treating hidradenitis suppurativa in both adults and some younger patients.
8 citations
,
September 2006 in “Transplantation” A kidney transplant and immunosuppressive treatment stopped the skin disease in a patient.
7 citations
,
October 2020 in “Journal of The American Academy of Dermatology” People with hidradenitis suppurativa have a higher risk of heart attacks and strokes.
6 citations
,
December 2022 in “International Journal of Molecular Sciences” Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.
6 citations
,
April 2013 in “British Journal of Dermatology” Hidradenitis suppurativa is likely caused by blocked hair follicles, not apocrine glands.
5 citations
,
March 2023 in “Archives of dermatological research” Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
5 citations
,
February 2022 in “Seminars in cell & developmental biology” Recent findings suggest that genetic factors, immune system issues, and skin cell defects might contribute to the development of hidradenitis suppurativa.
5 citations
,
July 2008 in “Journal of Cutaneous Pathology” The exact cause of hidradenitis suppurativa is unclear, but it may involve hair follicles, hormones, genetics, and smoking.
4 citations
,
December 2023 in “PubMed” Diet may help manage hidradenitis suppurativa symptoms.
4 citations
,
July 2023 in “Journal of Drugs in Dermatology” Hormonal treatments can effectively improve hidradenitis suppurativa symptoms.