research Cell-Laden Gel Biomimetic Skin Promotes Full-Thickness Skin Wound Regeneration
The new biomimetic skin heals wounds faster and better than traditional treatments, without scarring.
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research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerative Healing
Reprogramming adult fibroblasts may enable scar-free healing.
research Fibroblast Lineage Switching as the Developmental Origin of Scarring and Target for Regenerating Healing
Mimicking fetal wound environments may enable scarless healing in adults.
research The Rho GTPase regulator ARHGEF3 orchestrates hair placode budding by coordinating cell fate and P-cadherin patterning in mice
ARHGEF3 is essential for proper hair follicle development in mice.
research Ex vivo detection of SARS CoV 2 spike protein in human hair follicles and potential link to telogen effluvium
COVID-19 may cause hair loss by affecting hair follicles.
research The Role of PPARβ/δ-Related Lipid Metabolism in High-Altitude Adaptation of Yak Coat Based on Proteomics and Metabolomics
PPARβ/δ helps yaks adapt to high altitudes by regulating lipid metabolism in their coats.
research Iron–Skin Axis: Exploring the Interplay between Iron Homeostasis and Skin Disorders
Iron balance is crucial for skin health, affecting conditions like psoriasis and hair loss.
research Prediction of cell states and key transcription factors of the human cornea through integrated single-cell omics analyses
A new tool accurately identifies human cornea cell states and key factors.
research CXCL12 Drives Reversible Fibroimmune Remodeling in Androgenetic Alopecia Revealed by Single-Cell RNA Sequencing
Blocking CXCL12 can reverse hair loss and fibrosis in androgenetic alopecia.
research Network analysis reveals potential mechanisms that determine the cellular identity of keratinocytes and corneal epithelial cells through the Hox/Gtl2-Dio3 miRNA axis
Hox proteins help maintain keratinocyte identity by regulating miRNA expression.
research An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis
Basement membrane changes are crucial for hair follicle development.
research eLife assessment: Decoding the complexity of delayed wound healing following Enterococcus faecalis infection
Enterococcus faecalis delays wound healing by disrupting cell functions and creating an anti-inflammatory environment.
research Development of a novel in vitro strategy to understand the impact of shaving on skin health: combining tape strip exfoliation and human skin equivalent technology
The method effectively mimics shaving damage on skin for testing skincare products.
research Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development
Mechanical force is important for the first contact between skin cells and hair growth in mini-organs.
research Protein profiling of forehead epidermal corneocytes distinguishes frontal fibrosing from androgenetic alopecia
Protein profiling of forehead skin can help distinguish between frontal fibrosing alopecia and androgenetic alopecia.
research Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System
The AVET system effectively delivers genes to human keratinocytes and may help treat skin diseases.
research Advancements in Dermatological Imaging Modalities
The document reviews advancements in dermatological imaging modalities, emphasizing their potential to enhance diagnostic accuracy and reduce invasive procedures. Technologies like dermoscopy, OCT, RCM, and spectroscopy offer non-invasive diagnostic options for skin conditions, including cancer and hair issues, but face challenges such as high costs and the need for specialized training. Additional techniques like spectral imaging, thermography, and AI/ML are explored for their applications in skin cancer detection, therapeutic evaluation, and disease identification. Despite their benefits, these modalities are not confirmatory and may still require traditional methods for definitive diagnosis. Legal and infrastructural challenges also impact their adoption, particularly in countries like India.
research Molecular and Cellular Characterization of Avian Reticulate Scales Implies the Evo–Devo Novelty of Skin Appendages in Foot Sole
Bird foot scales develop differently and can repair but not fully regenerate due to the lack of specialized stem cell areas.
research Proteomic Analysis of Two Stem Cell Secretomes Used in Combination in a Topical Skin Care Product That Has Demonstrated Efficacy in a Double-Blinded, Vehicle-Controlled Clinical Trial
The combined stem cell secretome in the skin care product effectively reduces inflammation and promotes tissue regeneration.
research Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved Transcriptomics
Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
research EBS in Children with De Novo Pathogenic Variants Disturbing Krt14
Three specific genetic variants cause severe skin issues in children with EBS, highlighting the need for early genetic screening.
research Cytochrome P450: A Target for Drug Development for Skin Diseases
Modulating Cytochrome P450 activity could help develop new skin disease treatments.
research Three cDNA sequences of mouse type I keratins. Cellular localization of the mRNAs in normal and hyperproliferative tissues.
Different keratins have unique expression patterns in mouse skin cells.
research Aberrant expression of epidermal growth factor receptor in aural cholesteatoma
Cholesteatoma shows abnormal and increased EGF receptor expression, indicating its rapid growth.
research Heterogeneity of ornithine decarboxylase expression in 12-O-tetradecanoylphorbol-13-acetate-treated mouse skin and in epidermal tumors
ODC expression in mouse skin and tumors is varied and can be inhibited by retinoic acid or cycloheximide.
research Cornification in reptilian epidermis occurs through the deposition of keratin‐associated beta‐proteins (beta‐keratins) onto a scaffold of intermediate filament keratins
Reptile skin hardens by layering beta-proteins on keratin.
research Pemphigus Vulgaris Lacking Mucosal Involvement in a German Shepherd Dog: Possible Response to Heparin Therapy
Heparin treatment may help manage pemphigus vulgaris in dogs.
research Warty Dyskeratoma Involving Two Adjoining Follicles
A rare scalp tumor involving two hair follicles was successfully removed with surgery, with no recurrence after 7 months.
research Architecture of Reconstructed Epidermis on Collagen Lattices Varies according to the Method Used: A Comparative Study
The method and source of keratinocytes affect the structure of reconstructed skin.
research Rat hair follicle-constituting cells labeled by a newly-developed somatic stem cell-recognizing antibody: a possible marker of hair follicle development.
A3 antibody helps identify key cells in rat hair follicle development.