research Aging Skin: A Window to the Body
Skin aging reflects overall body aging and can indicate internal health conditions.
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research Human hair keratin hydrogel : fabrication, characterization and application
Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.
research Gender-linked differences in human skin
Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
research Direct conversion of mouse and human fibroblasts to functional melanocytes by defined factors
Fibroblasts can be turned into melanocytes for potential skin treatments.
research Anti-inflammatory role of 15-lipoxygenase contributes to the maintenance of skin integrity in mice
15-lipoxygenase helps keep skin healthy by reducing inflammation.
research SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair
SOX11 and SOX4 help skin cells act like embryonic cells to heal wounds in mice.
research Burn Reconstruction: the Problems, the Techniques, and the Applications
Burn reconstruction improves with new techniques, materials, and tissue engineering.
research Patched-assoziierte Tumoren: Modifikatorgene und Pathogenese
The document concludes that the development of certain tumors is influenced by genetic background and that a specific gene modification can lead to tumor regression and reduced growth.
research Prostaglandin D 2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research Differential Expression of Proteins Associated with the Hair Follicle Cycle - Proteomics and Bioinformatics Analyses
Researchers found 44 proteins that change during different hair growth stages and may be important for hair follicle function.
research Calreticulin: non‐endoplasmic reticulum functions in physiology and disease
Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
research Newborn infant skin gene expression: Remarkable differences versus adults
Newborn skin is uniquely prepared to adapt to new environments compared to adult skin.
research Alopecia - the search for novel agents continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells
Type II keratins are uniquely phosphorylated during stress and mitosis, affecting their structure and function.
research Targeted inactivation of integrin-linked kinase in hair follicle stem cells reveals an important modulatory role in skin repair after injury
Integrin-linked kinase is crucial for normal skin healing.
research Identification of Bulge Stem Cells in Mouse and Human Hair Follicles
Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
research Keratins and disease at a glance
Keratins are crucial for tissue strength, and mutations in keratin genes can lead to various diseases, highlighting the need for targeted therapies.
research Expression of keratins K6 and K16 in regenerating mouse epidermis is less restricted by cell replication than the expression of K1 and K10.
Keratins K6 and K16 are expressed more freely in regenerating mouse skin than K1 and K10.
research A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis
Skin cell behavior is influenced by the tightness of nearby cells, affecting their growth and development.
research Epidermal Stem Cells do not Communicate Through Gap Junctions
Epidermal stem cells don't use gap junctions to communicate.
research Neural Potential of a Stem Cell Population in the Hair Follicle
Stem cells in hair follicles can become various cell types, including neurons.
research WIF1 Is Expressed by Stem Cells of the Human Interfollicular Epidermis and Acts to Suppress Keratinocyte Proliferation
WIF1 helps keep skin stem cells inactive to prevent excessive cell growth.
research The malignant capacity of skin tumours induced by expression of a mutant H-ras transgene depends on the cell type targeted
The risk of skin tumors becoming malignant depends on the specific skin cell type affected.
research Hair follicle–derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma
Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research CUBIC Protocol Visualizes Protein Expression at Single Cell Resolution in Whole Mount Skin Preparations
The CUBIC protocol allows detailed 3D visualization of proteins in mouse skin biopsies.
research Differential epithelial outgrowth of plucked and microdissected human hair follicles in explant culture
research Involvement of Follicular Stem Cells in Forming Not Only the Follicle but Also the Epidermis
Hair follicle stem cells can form both hair follicles and skin.
research Unraveling the ECM-Immune Cell Crosstalk in Skin Diseases
Abnormal ECM and immune cell interactions can cause skin diseases.