research OVERCOMING THE BARRIERS TO EFFECTIVE DRUG DELIVERY TO THE BRAIN
New methods are being developed to improve drug delivery to the brain.
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480-510 / 1000+ results research Enhancing Solubility and Dissolution Behavior of Finasteride Using Solid Dispersion Technique by Carrier Screening and the New Preparation Instrument
research Effect of shampoo, conditioner and permanent waving on the molecular structure of human hair
Perming significantly changes hair's molecular structure, while shampoo and conditioner do not.
research The Application Progress of Tumor Microenvironment-Responsive Drug Carriers in Precision Chemotherapy
Tumor-targeted drug carriers can improve chemotherapy precision and reduce side effects.
research Iron-mediated DAMO–anammox process: Revealing the mechanism of electron transfer
Iron improves the DAMO-anammox process for treating water but too much iron can hinder it.
research Temperature-dependent phase transition microemulsions for enhanced transdermal delivery of finasteride and silodosin
Menthol-based microemulsions improve skin delivery of finasteride and silodosin.
research Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion
Charge-conversion chemistry improves hair-rebonding by enhancing penetration and strength.
research Effect of disulfide bonds in human hair fibers on the melting behavior of their crystalline structure
Disulfide bonds affect the melting behavior of hair's crystalline structure, but hair retains some stability even after these bonds are broken.
research Hair keratin molecular dynamics studies
Simulations of hair keratin help improve disease treatment and cosmetic products.
research Intracavity wavelength modulation of an optical parametric oscillator for coherent Raman microscopy
Researchers created a new light source that improves chemical imaging by removing background noise.
research Structure, atomic Hirshfeld surface, spectroscopic studies and magnetic and dielectric properties of new mixed solid solution (NH4 )2 Mn0.17 Cu0.83 Cl4 ⋅2H2 O
The compound (NH4)2Mn0.17Cu0.83Cl4.2H₂O has a specific structure, shows weak magnetism at low temperatures, and undergoes phase changes at high temperatures.
research Redefining Drug Discovery: A Review of Drug Repurposing –Approaches, Benefits and Breakthroughs
Drug repurposing finds new uses for existing drugs, speeding up treatment availability and reducing costs.
research An in-depth study of DOPE:DOPC liposomes to maximize targeted drug delivery to cancer-associated cells
DOPE:DOPC liposomes can improve targeted cancer drug delivery, reducing side effects and increasing effectiveness.
research De novo designed bifunctional proteins for targeted protein degradation
Newly designed proteins can effectively degrade specific proteins in cells, offering a promising alternative for targeted protein degradation.
research In-silico studies in herbal drugs: A review
Computational methods can speed up and improve the development and safety of herbal drugs.
research Nanotechnology in Cosmetics: An Overview
Nanotechnology improves cosmetics by enhancing ingredient delivery and effectiveness.
research Core-shell nanocarriers based on PEGylated hydrophobic hyperbranched polyesters
The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.
research The Interaction of Hair Fibers with Alkali Bromide Solutions
Hair absorbs alkali bromide salts and water, affecting its structure, with absorption decreasing at higher temperatures.
research Three-dimensional modelling of interchain sequence similarities and differences in the coiled-coil segments of keratin intermediate filament heterodimers highlight features important in assembly
Keratin heterodimers are preferred for their specific and structural advantages.
research Analysis of Cysteine on the Surface of Hair Fibers with Spectrofluorescence
Cysteine formation on hair indicates damage, best detected at pH 4.5.
research Aromatic C-nitrosation of a bioactive molecule. Nitrosation of minoxidil
Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.
research ChemInform Abstract: Discovery of a Novel Hybrid from Finasteride and Epristeride as 5α‐Reductase Inhibitor.
A new compound may effectively inhibit the enzyme linked to BPH and hair loss.
research Influence of functionalized silicones on hair fiber–fiber interactions and on the relationship with the macroscopic behavior of hair assembly
Functionalized silicones improve hair appearance, combing, and manageability.
research Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers?
New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
research Nanoemulsions for the Encapsulation of Hydrophobic Actives
Nanoemulsions can effectively improve the delivery of certain hydrophobic molecules.
research The role of disulfide bond formation in the structural transition observed in the intermediate filaments of developing hair
Disulfide bonds are crucial for hair structure during keratinization.
research Reduction mechanism of L ‐cysteine on keratin fibers using microspectrophotometry and Raman spectroscopy
L-cysteine slows down the breaking of bonds in hair due to electrostatic interactions.
research Rapidly Gelling Sprayable Hydrogels Integrating Carbon Quantum Dots and Plant Extracellular Vesicles Enable Multifunctional Wound Care via Photothermal Management, Immunomodulation, and Ferroptosis
A new sprayable hydrogel helps heal wounds faster and reduces inflammation.
research Cutaneous absorption of nanostructured chitin associated with natural synergistic molecules (Lutein)
Chitin nanofibrils can improve skin health and help deliver active ingredients into the skin.
research FeCl3-catalysed C-N coupling reaction between cyclic ethers and heterocyclic amines
Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.