research Gut Microbiota-Derived Exosomes Are Unique Natural Nanocarriers for Therapeutics
Gut microbiota-derived exosomes could be effective natural carriers for targeted drug delivery in personalized medicine.
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research Purification and characterization of an immuno-stimulatory compound from the water extract of royoporus badius (Pers.) A.B. De.
A new compound from Royoporus badius activates immune cells and induces inflammatory responses.
research 2-Substituted 4-(Thio)chromenone 6-O-Sulfamates: Potent Inhibitors of Human Steroid Sulfatase
New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
research Caractérisation physique et chimique des substances à activité thérapeutique : application aux études de profil de stabilité et de préformulation
APIs' stability is influenced by crystalline forms, pressure, and water.
research Recent advancements in wound management: Tailoring superwettable bio-interfaces
Superwettable bio-interfaces improve wound care by better managing fluids.
research Design and synthesis of potential nano-carrier for delivery of diphencyprone to hair follicle
research Polymeric nanoparticles-embedded organogel for roxithromycin delivery to hair follicles
Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
research Function and interactions of the Ysc84/SH3yl1 family of actin- and lipid-binding proteins
The Ysc84/SH3yl1 protein family is important for cell movement and the process of taking in materials by interacting with actin and cell membranes.
research A Comprehensive Review on Deep Eutectic Solvents and Its Use to Extract Bioactive Compounds of Pharmaceutical Interest
Deep eutectic solvents are eco-friendly and effective for extracting useful pharmaceutical compounds.
research Ligand Based 3D-QSAR Study on a Series of Steroidal Human 5α-Reductase Inhibitors
research Insights on the mechanical behavior of keratin fibrils
Keratin's mechanical properties are influenced by hydrogen bonds and secondary structure, and can be improved with the SPD-2 peptide.
research Crystal Structure of 17-.BETA.-Benzoyloxy-16-.BETA.-methylpregna-4,6-diene-3,20-dione.
A new antiandrogen compound was made and its detailed three-dimensional shape was described.
research Effect of liposomal fluidity on skin permeation of sodium fluorescein entrapped in liposomes
Increased liposome fluidity boosts skin penetration of sodium fluorescein.
research Colistin adorned topical nanoemulsion gel formulation for enhanced anti-microbial activity
The new gel improves treatment of tough skin infections.
research How Biodegradable Polymers Can be Effective Drug Delivery Systems for Cannabinoids? Prospectives and Challenges
Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.
research Exosomes facilitate mRNA and siRNA delivery using cationic liposomes 2X3-DOPE to rat heart mesenchymal cells in vitro
Modified liposomes with exosomes effectively deliver RNA to stem cells.
research The mechanisms and functions of interorganelle interactions
Different parts of cells interact at specific areas to control cell functions like energy production and fat storage.
research Formulation and evaluation of self-nanoemulsifying drug delivery system for improved oral delivery of exemestane hydrochloride
The new drug delivery system improves exemestane's absorption and effectiveness.
research Contents list
research Human hair keratin-associated proteins: Sequence regularities and structural implications
Keratin-associated proteins help link filaments and affect keratin's strength.
research Preparation, solubility, and anti-inflammatory effects of a complex of diphenylcyclopropenone/β-cyclodextrin derivatives as the treatment of alopecia areata
The DPCP/HPβCD complex improves solubility and anti-inflammatory effects for alopecia areata treatment.
research In vivo formation steps of the hard α-keratin intermediate filament along a hair follicle: Evidence for structural polymorphism
Hair follicles form hard α-keratin filaments in four steps, showing structural differences.
research Micropore-forming photocurable tissue adhesive promotes cell infiltration for wound healing
A new tissue adhesive helps wounds heal better by allowing more cells to enter.
research MULTIOMICS – A NEW EXCITING ERA OF RESEARCH
Multiomics is revolutionizing biology by enabling breakthroughs in research and disease diagnosis.
research Silver Oxide Based Nanoparticle Assisted Laser Desorption/Ionization Mass Spectrometry for the Detection of Low Molecular Weight Compounds
Silver oxide nanoparticles help detect small molecules effectively.
research Developing formulations designed to deliver antiseptic agents to target sites within the skin
Nanoemulsions can effectively deliver antiseptic agents deep into the skin.
research Author response: Structural basis of malodour precursor transport in the human axilla
The transporter protein SH1446 in Staphylococcus hominis is key to underarm odor production.
research Transdermal Liposomal Delivery Systems: Advantages, Applications, Challenges, and Prospects
Liposomal delivery systems improve drug absorption through the skin, offering potential for better treatments.
research Solid Lipid Nanoparticles (SLN): Method, Characterization and Applications
Solid lipid nanoparticles are promising for delivering various drugs and improving treatment effectiveness.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.