A 73-year-old woman's unusual hair loss and growth led to the discovery of a rare condition causing too much testosterone, which improved after her ovaries were removed.
October 2016 in “Journal of Case Reports” A rare ovarian tumor can occur without causing male-like symptoms.
61 citations
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September 1994 in “The Journal of Clinical Endocrinology and Metabolism”
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” Prostaglandin D2 increases testosterone production in skin cells through a process involving reactive oxygen species, which could be a new target for treating hair loss and other skin conditions driven by testosterone.
18 citations
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March 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.
1 citations
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January 2020 in “Elsevier eBooks” Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.
November 2023 in “JCEM Case Reports” A postmenopausal woman's excess male hormone symptoms improved after her ovaries were removed.
November 2023 in “Magna Scientia Advanced Research and Reviews” Trazodone might help reverse post finasteride syndrome.
11 citations
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May 2022 in “World Journal of Biological Chemistry” Progesterone may help trans women with breast development and health, but more research is needed.
16 citations
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February 2018 in “European Journal of Endocrinology” Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.
July 2023 in “Journal of the ASEAN Federation of Endocrine Societies” GnRH agonist effectively diagnoses and treats postmenopausal hyperandrogenism from ovarian sources.
40 citations
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November 2011 in “American Journal of Human Biology” Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.
3 citations
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March 2016 in “Phytotherapy Research” The new compound was more effective than finasteride in reducing markers of hair loss and prostate issues in cell tests.
September 2025 in “Journal of the American Academy of Dermatology” Sublingual minoxidil significantly improves hair growth in transgender individuals on testosterone therapy.
1 citations
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January 2023 in “Journal of Clinical Medicine” A new hair restoration technology was found to effectively increase hair thickness, density, and growth, while reducing hair loss and improving scalp health, with no side effects.
20 citations
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October 2017 in “Clinical Endocrinology” The conclusion is that removing both ovaries is the best treatment for excess male hormones in postmenopausal women, with medication as another option, and managing insulin resistance is important for diagnosis and treatment.
8 citations
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July 2017 in “The Journal of Steroid Biochemistry and Molecular Biology” DHT affects testicular development and regulates spermatogenesis in some fish.
11 citations
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January 2013 in “Indian Journal of Endocrinology and Metabolism” A woman with a rare adrenal tumor and hormonal disorder had improved testosterone levels after surgery, but her menstrual irregularities continued.
November 2022 in “Journal of the Endocrine Society” An 8-year-old boy's early puberty was caused by a rare hormone-secreting brain tumor, which was successfully treated with surgery.
18 citations
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March 2020 in “Frontiers in Neuroendocrinology” The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.
February 2010 in “ePrints Soton (University of Southampton)” Male sexual differentiation is regulated independently, while female differentiation occurs in an androgenic environment, affecting conditions like congenital adrenal hyperplasia.
74 citations
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January 2011 in “Reproductive Biology and Endocrinology” Testosterone therapy can improve hormone levels and quality of life in men with morphine-induced hormone issues.
Injecting patients' own PRP into their thyroid improved thyroid function and symptoms in most hypothyroidism cases.
2 citations
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April 2019 in “Journal of Internal Medicine” Men using steroids or finasteride to look more attractive may harm their fertility and sexual function, creating a paradox where they seem fit but may be less able to reproduce.
December 2023 in “ANNALS OF ABBASI SHAHEED HOSPITAL AND KARACHI MEDICAL & DENTAL COLLEGE” Spexin levels are lower in PCOS patients and linked to metabolic and hormonal issues.
April 2010 in “The Journal of Urology” The research found that androgens help control blood flow in the rat prostate through a specific binding site.
14 citations
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September 2017 in “General and comparative endocrinology” Barn owls with smaller black spots have higher testosterone levels, which might be due to genetic effects on hormone regulation rather than hormone effects on coloration.
55 citations
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June 2012 in “Steroids” Testosterone affects vascular cells directly without converting to estradiol.
April 2025 in “Al-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )” Cuscuta reflexa extract may help treat benign prostatic hyperplasia by reducing inflammation and oxidative stress.
19 citations
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June 2021 in “The world journal of men's health” Using anabolic-androgenic steroids can harm men's reproductive health and increase the risk of heart problems and death.