92 citations
,
August 2017 in “Proceedings of the National Academy of Sciences of the United States of America” Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.
239 citations
,
December 2013 in “Scientific Reports” A new method quickly creates controllable cell clusters for tissue engineering and drug testing.
194 citations
,
May 2000 in “Journal of Investigative Dermatology” The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.
113 citations
,
June 2015 in “Stem Cell Research & Therapy” Wnt and Notch signaling help wound healing by promoting cell growth and regulating cell differentiation.
94 citations
,
September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
79 citations
,
January 2015 in “Journal of Materials Chemistry B” Smart biomaterials that guide tissue repair are key for future medical treatments.
67 citations
,
December 2008 in “Developmental Biology” Msx2 and Foxn1 are both crucial for hair growth and health.
61 citations
,
May 2016 in “Scientific reports” The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.
51 citations
,
November 2013 in “Drug Discovery Today” Small molecule drugs show promise for advancing regenerative medicine but still face development challenges.
51 citations
,
January 1989 in “Journal of Investigative Dermatology” Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.
48 citations
,
April 2024 in “Nature Communications” The new method improves bone repair by enhancing cell loading and stability in bioprinted scaffolds.
43 citations
,
July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
43 citations
,
August 2008 in “Regenerative Medicine” Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
42 citations
,
December 2016 in “Cell Death & Differentiation” Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.
36 citations
,
August 2021 in “Nature Cell Biology” Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
30 citations
,
December 2017 in “Advanced Healthcare Materials” Nanoencapsulation creates adjustable cell clusters for hair growth.
23 citations
,
June 2012 in “Molecular Biology Reports” VEGF stimulates hair cell growth and increases growth receptor levels through a specific signaling pathway.
10 citations
,
May 2007 in “Oncology Reports” Colorectal cancer's ability to spread is due to changes in many genes, not just one.
9 citations
,
January 2006 in “Cutaneous and ocular toxicology” L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.
6 citations
,
February 2013 in “Journal of Visualized Experiments” The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
4 citations
,
January 2015 in “Hair therapy & transplantation” Hair follicle stem cells could be used to treat the skin condition vitiligo.
3 citations
,
August 2014 in “Steroids” Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.
3 citations
,
January 2014 in “Elsevier eBooks” Different stem cells have benefits and challenges for tissue repair, and more research is needed to find the best types for each use.
2 citations
,
April 2021 in “International Journal of Pharmaceutics” Serum formulations were better at delivering molecules to the hair bulb than nanoparticles.
2 citations
,
January 2008 in “Elsevier eBooks” Humans have limited regenerative abilities, but new evidence shows the adult brain and heart can regenerate, and future treatments may improve this by mimicking stem cell environments.
1 citations
,
November 2014 in “Elsevier eBooks” Future research should focus on making bioengineered skin that completely restores all skin functions.
September 2025 in “Arthritis Research & Therapy” BMS-470539 reduces skin fibrosis and inflammation.
June 2022 in “Research Square (Research Square)” Hair follicle stem cells can help heal intestinal injuries in rats.
Biofield Energy Healing significantly increased hair growth by making hair root cells grow more.
January 2018 in “Open access journal of pharmaceutical research” Biofield Energy Healing may increase hair growth by enhancing cell proliferation.