research Before & beyond the pain – Allostatic load, central sensitivity and their role in health and function
Recognizing and managing central sensitization and stress is crucial for treating chronic pain.
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research 521 Deciphering Pathomechanisms in Solar Urticaria
The study found that skin inflammation and immune response pathways are activated in Solar Urticaria patients after UV exposure, unlike in healthy people.
research The effect of hormones of the hypothalamic-pituitary-target gland axes in a kidney-yang deficiency syndrome model
Kidney-yang deficiency syndrome causes hormonal imbalances and various physical symptoms.
research PSYCHOCUTANEOUS MEDICINE: PRESENT STATUS AND TRENDS OF INQUIRY
The current state and future directions of the field that studies the connection between the mind and skin are discussed.
research 196 The endocannabinoid tone regulates human sebocyte biology
The endocannabinoid system affects oil production and inflammation in skin cells.
research Sensitive skin
Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.
research Single-Cell RNA Sequencing Reveals Cellular and Transcriptional Changes Associated With M1 Macrophage Polarization in Hidradenitis Suppurativa
Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
research Hormesis and medicine
Low doses of some substances can be beneficial, while high doses can be harmful or toxic.
research Transcutaneous Auricular Vagus Nerve Stimulation Alleviates Monobenzone-Induced Vitiligo in Mice
taVNS reduces vitiligo symptoms in mice.
research 087 Basal-to-inflammatory transition and tumor resistance via crosstalk with a pro-inflammatory stromal niche
research Interaction between stem cell factor and endothelin-1: effects on melanogenesis in human skin xenografts
SCF and ET-1 together significantly increase skin pigmentation and melanin production.
research [The function of the autonomic nervous system in women with androgenetic alopecia].
Women with androgenetic alopecia have noticeable changes in their autonomic nervous system.
research PBX1-SIRT1 positive feedback loop attenuates ROS-mediated HF- MSC senescence and apoptosis
PBX1 reduces aging and cell death in stem cells by boosting SIRT1 and lowering PARP1.
research 804 Human hair follicles operate core elements of a functional peripheral equivalent of the central hypothalamic-pituitary-thyroid axis
Human hair follicles have their own thyroid hormone system.
research Empathic disequilibrium is related to lower levels of oxytocin in hair
People with an imbalance between their cognitive and emotional empathy have lower levels of the hormone oxytocin in their hair.
research The human hair follicle has established a fully functional peripheral equivalent of the hypothamalic‐pituitary‐adrenal‐axis (HPA)
Human hair follicles can produce stress hormones like the body's main stress response system.
research A simple immunofluorescence technique for simultaneous visualization of mast cells and nerve fibers reveals selectivity and hair cycle - dependent changes in mast cell - nerve fiber contacts in murine skin
Mast cell and nerve fiber interactions in mouse skin change with the hair cycle.
research Mechanical stimulation of human hair follicle outer root sheath cultures activates adjacent sensory neurons
Touching hair can activate nearby nerve cells through signals from the hair's outer layer.
research Hair melanocytes as neuro-endocrine sensors—Pigments for our imagination
Hair melanocytes help the skin respond to stress and regulate hair pigmentation.
research Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide‐osmium tetroxide technique
Methylene blue staining effectively reveals detailed nerve structures in rat snouts.
research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man
research Comparison of the Pathology of Fascia in Eosinophilic Myalgia Syndrome Patients and Idiopathic Eosinophilic Fasciitis
EMS and EF both show similar skin and fascia changes, but EMS has more severe symptoms and nerve inflammation.
research An implication for post-transcriptional control: Reciprocal changes of melanocortin receptor type 2 mRNA and protein expression in alopecia areata
Alopecia areata may involve stress-related changes affecting hormone receptors, leading to reduced cortisol production.
research Increased acetylcholine levels in skin biopsies of patients with atopic dermatitis
Atopic dermatitis patients have much higher acetylcholine levels in their skin, which may cause itching.
research 1618 Simulated solar radiation (SSR) induced skin inflammation across skin types measured by dynamic optical coherence tomography and laser doppler
Sunlight simulation causes skin inflammation, with different skin types reacting at different levels of exposure.
research Relationships between hair-follicle afferent axons and glycine-immunoreactive profiles in cat spinal dorsal horn
Aδ-LTMRs have complex synapses with glycine, while Aβ-LTMRs have simpler ones.
research Classic Sweet sydrome: A case report
A 54-year-old man with painful skin blisters and fever was diagnosed with Sweet syndrome and successfully treated with corticosteroids.
research THE ROLE Of 5αR AND α1AR INHIBITORS IN MANAGEMENT OF BPH
Combining dutasteride or finasteride with an α1 blocker is more effective for managing BPH than using either alone.
research 772 Alopecia areata shares OX40 activation and Th1 and Th2 increases across atopic backgrounds
research Characteristic intraepidermal nerve fibre endings of the intervibrissal fur in the mystacial pad of the rat: morphological details revealed by intravital methylene blue staining and the zinc iodide-osmium tetroxide technique
Methylene blue staining effectively highlights detailed nerve structures in rat fur.