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Ionizable Coenzyme-Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases

research Ionizable Coenzyme‐Engineered Lipid/Fiber Microplexes Boost Ribosomal Translation to Improve mRNA Therapy for Degenerative Diseases

October 2025 in “Advanced Materials”

New lipid/fiber microplexes improve mRNA therapy for degenerative diseases by enhancing cell function and treatment effectiveness.

research A novel pathogenic variant of NECTIN4 gene in a child with ectodermal dysplasia-syndactyly syndrome

January 2023 in “Indian dermatology online journal”

A child with ectodermal dysplasia-syndactyly syndrome has a new mutation in the NECTIN4 gene.

research Selective Expression of Calcium-Binding Proteins S100A8 and S100A9 at Distinct Sites of Hair Follicles

22 citations , September 2001 in “Journal of Investigative Dermatology”

S100A8 and S100A9 proteins help form hair shafts during growth.

research Cleave but not leave: Astrotactin proteins in development and disease

8 citations , May 2017 in “IUBMB life”

Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.

research Neurotoxins Acting at Synaptic Sites: A Brief Review on Mechanisms and Clinical Applications

5 citations , December 2022 in “Toxins”

Neurotoxins can affect neurotransmitter release and have potential in treating muscle, pain, and cancer conditions, but more research is needed on how they work.

research Structural Transition of Trichocyte Keratin Intermediate Filaments During Development in the Hair Follicle

7 citations , January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry”

research Analysis of the sheep trichohyalin gene: potential structural and calcium-binding roles of trichohyalin in the hair follicle.

72 citations , May 1993 in “The Journal of Cell Biology”

Trichohyalin in sheep hair follicles may help with structure and calcium binding.

Expression Patterns of Glial Cell Line-Derived Neurotrophic Factor, Neurturin, Their Cognate Receptors GFRα-1, GFRα-2, and Common Signal Transduction Element c-Ret in Human Skin Hair Follicles

research Expression patterns of the glial cell line–derived neurotrophic factor, neurturin, their cognate receptors GFRα-1, GFRα-2, and a common signal transduction element c-Ret in the human skin hair follicles

18 citations , January 2008 in “Journal of The American Academy of Dermatology”

Certain proteins and their receptors are more active during the growth phase of human hair and could be targeted to treat hair disorders.

research 876 Imaging nanoscale changes in desmosome protein organization

April 2018 in “Journal of Investigative Dermatology”

Desmoglein 3 organization in cell connections changes without calcium, affecting cell adhesion.

Atypical Hippocampal Glutamate Receptor Coupled to Phospholipase D Controlling Stretch-Sensitivity in Primary Mechanosensory Nerve Endings Is Homomeric Purely Metabotropic GluK2

research The atypical ‘hippocampal’ glutamate receptor coupled to phospholipase D that controls stretch‐sensitivity in primary mechanosensory nerve endings is homomeric purely metabotropic GluK2

6 citations , September 2023 in “Experimental physiology”

A special receptor in sensory nerve endings helps control how they respond to stretching.

research Characterization of the cysteine-rich calcium-binding S100A3 protein from human hair cuticles

17 citations , December 2002 in “Biochemical and biophysical research communications”

Scientists found out how a specific protein in human hair cuticles behaves and is structured.

research Saccharomyces cerevisiae BLYAS, a New Bioluminescent Bioreporter for Detection of Androgenic Compounds

66 citations , August 2007 in “Applied and environmental microbiology”

The engineered yeast strain BLYAS can quickly and sensitively detect androgenic chemicals.

research The calcium-binding protein calretinin is a marker of the companion cell layer of the human hair follicle

26 citations , June 2005 in “British Journal of Dermatology”

Calretinin identifies the companion cell layer in human hair follicles.

research An Updated Nomenclature for Keratin-Associated Proteins (KAPs)

92 citations , January 2012 in “International Journal of Biological Sciences”

The document introduced a new naming system for keratin-associated proteins to improve clarity and communication across species.

research Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21

37 citations , January 1993 in “Journal of Investigative Dermatology”

research Identification of an osteopontin-derived peptide that binds neuropilin-1 and activates vascular cells

September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)”

FOL-026 peptide can help repair blood vessels and promote growth, offering potential treatment for vascular diseases.

research Dynamic expression patterns of tenascin, proteoglycans, and cell adhesion molecules during human hair follicle morphogenesis

67 citations , February 1994 in “Developmental dynamics”

Specific proteins and molecules play key roles in the development of human hair follicles.

research KCNQ4 K+ channels tune mechanoreceptors for normal touch sensation in mouse and man

109 citations , November 2011 in “Nature Neuroscience”

research Tissue microarray를 이용한 사이모신 베타4(Thymosin β4)와 vascular endothelial cell growth factor (VEGF)의 정상 인간 조직 발현 양상 연구

December 2009 in “생명과학회지”

Thymosin β4 and VEGF are important for organ function and may help with blood vessel formation.

research BMP4 and nuclear laminC orchestrate a expression of AHF/Trichohyalin molecule, a key modulator of keratin intermediate filaments in the hair follicle

January 2007

A Spontaneous Fatp4/Slc27a4 Splice Site Mutation in a New Murine Model for Congenital Ichthyosis

research A Spontaneous Fatp4/Scl27a4 Splice Site Mutation in a New Murine Model for Congenital Ichthyosis

13 citations , November 2012 in “PLoS ONE”

A gene mutation in mice causes severe skin disorder similar to a human condition.

research Some observations on the proteins of the inner root sheath cells of hair follicles

34 citations , July 1958 in “Biochimica et Biophysica Acta”

research Overexpression of the 18 kDa translocator protein (TSPO) in the hippocampal dentate gyrus produced anxiolytic and antidepressant-like behavioural effects

25 citations , June 2017 in “Neuropharmacology”

Increasing TSPO in the brain reduces anxiety and depression.

research Evolutionary Trees of Intermediate Filament Proteins

3 citations , January 1988

research Biochemical Evidence That Small Proline-rich Proteins and Trichohyalin Function in Epithelia by Modulation of the Biomechanical Properties of Their Cornified Cell Envelopes

99 citations , May 1998 in “Journal of biological chemistry/The Journal of biological chemistry”

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

research Two novel MBTPS2 missense mutations impairing S2P proteolytic activity lead to IFAP syndrome with new phenotypic anomalies

October 2023 in “Journal of dermatological science”

New mutations in MBTPS2 reduce its function and cause IFAP syndrome with unusual symptoms.

research Giant pigmented tumour of the scalp—a diffuse neurofibroma or a congenital naevus showing neurofibromatous changes? Immunohistochemical and electron microscopic studies

12 citations , August 1988 in “Histopathology”

The tumor likely shows dual neural crest differentiation.

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