46 citations
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May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
45 citations
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August 2005 in “Bioorganic & medicinal chemistry” New compounds with carborane showed anti-androgen effects similar to flutamide.
24 citations
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May 2015 in “Schizophrenia Research” A drug improved schizophrenia-like symptoms in stressed rats by changing brain steroid levels.
20 citations
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September 1983 in “Archives of dermatology” The new synthetic retinoid RO 13-6298 effectively treated severe psoriasis at low doses with manageable side effects.
16 citations
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March 2020 in “Animal Biotechnology” Transgenic sheep embryos with a specific promoter were successfully created, but more research is needed for gene expression in hair follicles.
14 citations
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November 2014 in “European journal of medicinal chemistry” Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
9 citations
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June 2023 in “Cells” Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
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April 2018 in “Biology of reproduction” Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
4 citations
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December 2024 in “European Journal of Medicinal Chemistry” New pyrazole-based inhibitors show promise for treating metabolic diseases and other conditions.
3 citations
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August 2017 in “Synlett” Scientists in India found a safer and efficient way to make a type of medicine called hydantoins from carbamates, which also worked well in making the seizure medicine, Ethotoin.
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September 1975 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” Pigs can make some essential fats and don't need them all in their diet to grow and stay healthy.
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May 2020 in “Molecules” A new, efficient method was developed to synthesize a specific compound and its derivatives.
2 citations
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August 2019 in “Turkish Journal of Chemistry” Researchers made minoxidil efficiently using cobalt ferrite nanoparticles as a reusable catalyst.
July 2024 in “Journal of Investigative Dermatology” New steroid derivatives show promise as anticancer agents, even against resistant cells.
Researchers made new compounds that could potentially be developed into anticancer drugs.
January 2017 in “Rasayan journal of Chemistry” Researchers created a new, efficient way to make Dutasteride, a hair loss and prostate drug, with high purity using a benzoyl group.
The research created new azasteroids and pseudoazulenyl nitrones, which could be useful in medicine.
January 2011 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” New molecules can prevent cell death in hair follicles.
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January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
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September 1996 in “PubMed” Desmocollin 1 and 3 have distinct patterns in human tissues, with Dsc1 in specific skin and hair layers and Dsc3 in various epithelial layers.
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December 2004 in “Choice Reviews Online” The document summarized how various modern drugs are made.
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May 2011 in “Journal of Neuroendocrinology” PEA boosts allopregnanolone production and reduces oxidative stress in brain cells.
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February 1996 in “Journal of Investigative Dermatology” Polyamines, especially spermidine, are essential for hair growth.
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May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
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April 1988 in “Archives of Dermatological Research” 23 citations
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October 2008 in “Journal of medicinal chemistry” PF-998425 is a new, effective, and non-phototoxic treatment for skin conditions related to androgens.
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October 2015 in “Neurochemistry International” Letrozole may help prevent seizures by reducing certain hormone levels.
14 citations
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May 2013 in “American Journal of Physiology-endocrinology and Metabolism” Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
13 citations
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October 2007 in “Bulletin of the Korean Chemical Society” Mollugin may help treat diseases and boost hair growth and anti-aging.