research Tissue Expansion in Cicatricial Alopecia
Tissue expansion is an effective treatment for certain types of hair loss, providing immediate coverage with hair-bearing skin.
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570-600 / 1000+ results research Subcellular localization of the five members of the human steroid 5α-reductase family
All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.
research Generation of comparative pharmacophoric model for steroidal 5α-reductase I and II inhibitors: A 3D-QSAR study on 6-azasteroids
The study created a model to help design new inhibitors for steroidal 5α-reductase enzymes.
research Diseases on Hair Follicles Leading to Hair Loss Part I: Nonscarring Alopecias
Common types of non-scarring hair loss have various causes and treatments, but more effective solutions are needed.
research Comparative transcriptome profiling provides new insights into mechanisms of androgenetic alopecia progression
AGA progression involves increased lipid synthesis, electron transport, and hair follicle miniaturization.
research Recalcitrant alopecia areata responsive to leflunomide and anthralin—Potentially undiscovered JAK /STAT inhibitors?
Leflunomide and anthralin may effectively treat severe alopecia areata.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
A new non-invasive method can analyze skin mRNA to understand skin diseases better.
research Case report: pemphigus vulgaris in an adolescent
An 18-year-old girl with pemphigus vulgaris needed strong medication and careful treatment due to ineffective initial therapies and side effects.
research RECENT DEVELOPMENTS IN ALOPECIAS
Recent hair loss research shows some progress, especially in understanding male pattern baldness, but effective treatments for many types of hair loss are still lacking.
research Acne in Dark Skin
Acne in dark skin is influenced by environmental factors and can lead to hyperpigmentation, with various treatment options available.
research Mild Cutaneous Manifestation in Two Young Women with Extraordinary Hyperandrogenemia
Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.
research Mapping of cis-acting expression quantitative trait loci in human scalp hair follicles
Researchers identified genes in scalp hair follicles that may affect hair traits and hair loss.
research Mechanisms of Puerariae Lobatae Radix in regulating sebaceous gland secretion: insights from network pharmacology and experimental validation
Puerariae Lobatae Radix can reduce sebaceous gland size and secretion, potentially treating related skin conditions.
research Alterations in Pattern Baldness According to Sex: Hair Metabolomics Approach
Hair loss causes differ between men and women due to changes in hormone levels and inflammation-related pathways.
research Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome
Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
research Current and future pharmacotherapy for alopecia areata
New treatments for hair loss show promise but need more research to confirm safety and effectiveness.
research Clinical Impact of Molecular Diagnostics in Endocrinology
Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.
research Non-invasive human skin transcriptome analysis using mRNA in skin surface lipids
The conclusion is that analyzing RNA from skin oils is a promising way to understand skin diseases.
research The Polycystic Ovary Syndrome and Acne
Polycystic Ovary Syndrome (PCOS) often leads to severe acne, and lifestyle changes and hormonal treatments can help manage it.
research IMPACT OF MERCURY ON SEX HORMONES (LITERATURE REVIEW)
Mercury can disrupt sex hormones and cause reproductive issues.
research Regulatory Effects of Thai Rice By-Product Extracts from Oryza sativa L. cv. Bue Bang 3 CMU and Bue Bang 4 CMU on Melanin Production, Nitric Oxide Secretion, and Steroid 5α-Reductase Inhibition
BB4CMU rice bran oil may help treat hair loss and gray hair.
research Prolonged use of finasteride-induced gonadal sex steroids alterations, DNA damage and menstrual bleeding in women
Long-term use of finasteride in women can cause hormonal changes, DNA damage, and menstrual issues.
research A Teenage Girl with Unexpected Pubertal Changes
The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.
research Mitochondrial dysfunction in an animal model of diabetic neuropathy is associated with a reduction of neurosteroid synthesis.
Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.
research Treatment guidelines in adult women
Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.
research Ursolic acid, a pentacyclic triterpene from Ochrosia elliptica Labill leaves and its role in the management of polycystic ovary syndrome (PCOS)
Ursolic acid from Ochrosia elliptica leaves may help manage PCOS symptoms.
research Finasteride-Induced Neuropsychiatric Reactions
Finasteride can cause serious mental health issues, so it's advised to avoid it for hair loss.
research Radiotherapy-Induced Skin Fibrosis: Pathophysiology, Emerging Therapeutics, and the Role of Dermatology
Radiotherapy can cause skin fibrosis, which is often overlooked and needs better treatment and evaluation.
research Treatment Outcomes of Triamcinolone Acetonide Compared with Cryotherapy in Alopecia Areata: Evidence from a Systematic Review and Meta-Analysis
Triamcinolone acetonide is more effective than cryotherapy for hair regrowth in alopecia areata but has different side effects.
research Ichthyosis in Unani Medicine: A Comprehensive Review of Disorders of Cornification and their Modern Dermatological Correlates
Unani medicine and modern dermatology both offer treatments for ichthyosis, a condition causing dry, scaly skin.