research Geriatric Dermatology: Overview
Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.
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research Live imaging of skin immunity using two-photon microscopy: a short review
Two-photon microscopy improves skin imaging but faces safety and cost challenges for clinical use.
research Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche
Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.
research High proliferation and delamination during skin epidermal stratification
High proliferation and cell delamination drive early skin development, while later stages may not rely on cell division orientation.
research Novel therapeutic approaches in utilizing platelet lysate in regenerative medicine: Are we ready for clinical use?
Platelet lysate is a promising, cost-effective option for regenerative medicine with potential clinical applications.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
research Live imaging of stem cells: answering old questions and raising new ones
Live imaging has advanced our understanding of stem cell behavior and raised new research questions.
research Deciphering principles of morphogenesis from temporal and spatial patterns on the integument
The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
research Proliferation, DNA repair and apoptosis in androgenetic alopecia
Bald areas have lower cell growth, more DNA damage, and increased cell death.
research Spatio-temporal regulation of gene expression defines subpopulations of epidermal stem cells
Different types of skin stem cells can change and adapt, which is important for developing new treatments.
research Translational frontiers: insight from lymphatics in skin regeneration
Lymphatic vessels are important for skin repair and could affect skin disease treatments.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Use in Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research The Hair Follicle as a Dynamic Miniorgan
Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
research Apoptosis in human skin development: Morphogenesis, periderm, and stem cells
Apoptosis is essential for human skin development and forming a functional epidermis.
research Intradermal adipocytes mediate fibroblast recruitment during skin wound healing
Fat cells help recruit healing cells and build skin structure during wound healing.
research Defining dermal adipose tissue
Skin fat cells help with skin balance, hair growth, and healing wounds.
research More than one way to skin . . .
Skin stem cells help repair damage and maintain healthy skin.
research Prostaglandin D 2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia
PGD2 stops hair growth and is higher in bald men with AGA.
research A matter of life and death: self‐renewal in stem cells
Stem cell self-renewal is complex and needs more research for full understanding.
research Hierarchical patterning modes orchestrate hair follicle morphogenesis
Hair follicle patterns form through a mix of self-organization and signaling interactions.
research Human skin stem cells and the ageing process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Human Epidermal Neural Crest Stem Cells (hEPI-NCSC)—Characterization and Directed Differentiation into Osteocytes and Melanocytes
Human epidermal neural crest stem cells can become bone and skin pigment cells, making them useful for therapies.
research Stem cells and the circadian clock
The circadian clock influences the behavior and regeneration of stem cells in the body.
research Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog
Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
research The Senescence–Stemness Alliance – A Cancer-Hijacked Regeneration Principle
Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
research New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence
The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
research Mechanical forces in skin disorders
Skin problems can be caused or worsened by physical forces and pressure on the skin.
research Emerging nonmetabolic functions of skin fat
Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.
research Androgen Action in the Ovary
Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.
research Physiological Regeneration of Skin Appendages and Implications for Regenerative Medicine
The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.