research Proteolysis‐targeting chimeras in cancer therapy: Targeted protein degradation for next‐generation treatment
PROTACs offer a new, precise way to treat cancer by breaking down harmful proteins.
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660-690 / 1000+ resultsresearch Recent Insights in Multi‐Target Drugs in Pharmacology and Medicinal Chemistry
Multitarget drugs are needed to better treat complex diseases.
research Enhancing alopecia areata management: Nanocrystal-driven strategy for targeting hair follicles
Nanocrystals improve alopecia areata treatment by better targeting hair follicles.
research Characterisation of Three Ovine KRTAP13 Family Genes and Their Association with Wool Traits in Chinese Tan Sheep
An allele of the KRTAP13-2 gene may improve wool quality in sheep.
research Proteomic Analysis of Crimped and Straight Wool in Chinese Tan Sheep
Crimped wool has proteins linked to crimp formation, while straight wool has proteins linked to fiber fineness, which can improve wool quality and value.
research γδ T Cells Mediate a Requisite Portion of a Wound Healing Response Triggered by Cutaneous Poxvirus Infection
γδ T cells are essential for wound healing after poxvirus infection.
research Drugs targeting epithelial–mesenchymal transition molecules for treatment of lichen planopilaris
Drugs targeting EMT molecules show promise for treating lichen planopilaris.
research Nanostructured Drug Delivery Systems for Targeting 5-α-Reductase Inhibitors to the Hair Follicle
Nanostructured delivery systems could potentially improve hair loss treatment by targeting drugs to hair follicles, reducing side effects and dosage, but the best size, charge, and materials for these systems need further investigation.
research Faun tail nevus: A series of 15 cases and their management with Intense Pulse Light
Intense Pulse Light effectively reduces hair growth in faun tail nevus.
research New multi-targeting strategy in hair growth promotion: in vitro and in vivo studies
The lotion with N1-methylspermidine and Sandalore® effectively reduces hair loss and promotes hair growth.
research Extractives of Cercidiphyllum japonicum twigs: isolation and structural elucidation of a new galloylflavonol glycoside, anomeric tannins and flavonoids
Scientists found a new natural compound and other known compounds in Cercidiphyllum japonicum twigs, which might be useful for medicine.
research Liquid chromatographic-mass spectrometric method for determination of drug content uniformity of two commonly used dermatology medications in a split-tablet dosage form
Splitting non-scored tablets can lead to uneven drug distribution, posing risks.
research Biotechs target stagnant baldness market
New drug shows promise for better hair growth in baldness treatment.
research CLINICAL EVALUATION OF HAIRBAC TABLET AND OIL IN THE MANAGEMENT OF DIFFUSE HAIR LOSS: AN OPEN CLINICAL STUDY
Hairbac tablet and oil significantly improve hair texture, density, and reduce hair loss without side effects.
research Atrichia with papular lesions in a Taiwanese patient without hairless (HR) gene mutation
A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.
research Empagliflozin targeting STAT3/Akt/Nrf2 axis promoting diabetic wound healing in rat model
Empagliflozin helps heal diabetic wounds in rats by reducing inflammation and oxidative stress.
research Cytokine-Targeting Biologic Therapies for Alopecia Areata: A Comprehensive Review of Mechanism of Action, Clinical Efficacy, and Adverse Events
Dupilumab and ustekinumab are promising treatments for alopecia areata, showing significant hair regrowth.
research A cannabinoid Hairy‐Tale : Hair loss or hair gain?
CBD may increase hair growth, but the right concentration is crucial and more research is needed.
research The Applications of Medical Tattooing in the Head and Neck Region
Medical tattooing improves appearance and quality of life, but has potential risks.
research An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of dehydroepiandrosterone sulfate in human serum and plasma
A new method accurately measures DHEAS in blood, improving on current tests.
research Sustaining treatment response in alopecia areata through tofacitinib dose tapering: A single-center retrospective study
research The pink tax: gender-based cost disparities of topical minoxidil
Women's minoxidil products cost more and are less effective than men's.
research Assessment of long-term alopecia after adjuvant taxane therapy for early breast cancer: a cross-sectional survey
Docetaxel chemotherapy causes more long-term hair loss and dissatisfaction than paclitaxel.
research Therapeutic targeting of ocular diseases with emphasis on PI3K/Akt, and OPRL pathways by Hedera helix L. saponins: a new approach for the treatment of Pseudomonas aeruginosa-induced bacterial keratitis
PEVIII is a promising treatment for Pseudomonas aeruginosa keratitis.
research Efficacy and safety of dual-targeted therapy for refractory inflammatory bowel disease: a retrospective case series from three tertiary general hospitals in China
Dual-targeted therapy is effective and safe for difficult-to-treat inflammatory bowel disease.
research Variation in Ovine KRTAP13-3 and Its Association with Wool Characteristics in Chinese Tan Sheep
The KRTAP13-3 gene affects wool fibre diameter variability in Chinese Tan sheep.
research Characterisation of Ovine KRTAP19-3 and Its Impact on Wool Traits in Chinese Tan Sheep
Specific gene variants affect wool traits in Chinese Tan sheep.
research 42004 Scalp, eyebrow, and eyelash hair regrowth with continued ritlecitinib treatment among patients with alopecia areata without target efficacy response at Week 24: post hoc analysis of the ALLEGRO phase 2b/3 study
Continued ritlecitinib treatment can lead to hair regrowth in some patients with alopecia areata who initially don't respond.
research DKK1-targeting cholesterol-modified siRNA implication in hair growth regulation
Blocking DKK1 with siRNA can improve hair growth.
research Cytokine-targeted treatment in alopecia areata - new possibilities?
New cytokine-targeted therapies show promise for treating alopecia areata.