3 citations
,
October 2024 in “International Journal of Molecular Sciences” Xenopus laevis tadpoles can regenerate complex tail structures, offering insights for regenerative medicine.
March 2025 in “Multidisciplinary Science Journal” Sonic hedgehog (Shh) is crucial for gecko tail regeneration.
228 citations
,
September 2012 in “Trends in Neurosciences” Nerves are crucial for the regeneration of various body parts in many animals.
26 citations
,
August 1971 in “Journal of Morphology” Lizards can regrow their tail scales with the same structure, distribution, and gender-specific features as the original ones, and this unique ability is not seen in adult mammals.
June 2020 in “Journal of Investigative Dermatology” The technique effectively shows how human skin and hair cells form into ball-like structures.
January 2011 in “대한피부과학회지” A 7-year-old girl was diagnosed with trichothiodystrophy due to low sulfur levels in her hair.
39 citations
,
April 2015 in “Regeneration” Lizards can regrow their tails, and studying this process helps understand scar-free healing and limb regeneration.
201 citations
,
April 2017 in “Regeneration” Macrophages and fibroblasts help repair organs after injury, affecting whether they regenerate or scar.
37 citations
,
April 2015 in “Development Growth & Differentiation” The Hippo signaling pathway helps control organ size during regeneration by regulating gene expression.
60 citations
,
April 2012 in “Physiology” The document concludes that understanding hair and feather regeneration can help develop new regenerative medicine strategies.
418 citations
,
September 2012 in “Nature” African spiny mice can regenerate skin, hair, and cartilage, but not muscle, and their unique abilities could be useful for regenerative medicine.
19 citations
,
November 2018 in “Experimental Dermatology” The spiny mouse can regenerate its skin without scarring, which could help us learn how to heal human skin better.
17 citations
,
September 2019 in “Journal of Cell Biology” Hair follicle regeneration may slow tumor growth.
13 citations
,
March 1998 in “Journal of Biomedical Materials Research” Island grafts can help study skin regeneration separately from other healing processes.
6 citations
,
February 2013 in “Journal of Visualized Experiments” The method quickly analyzes hair growth genes and shows that blocking Smo in skin cells stops hair growth.
1 citations
,
November 2017 The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.
85 citations
,
December 2017 in “Developmental Biology” Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.
44 citations
,
January 2019 in “Journal of Translational Medicine” Macrophages are essential for successful skin growth in reconstructive surgery.
19 citations
,
June 2008 in “Journal of Investigative Dermatology” HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
9 citations
,
November 2018 in “Drug Discovery Today” Using skin stem cells and certain molecules might lead to scar-free skin healing.
1 citations
,
September 2023 in “eLife” TLR2 is important for hair growth and can be targeted to treat hair loss.
16 citations
,
January 2011 in “Archives of Dermatological Research” The study found that expanded skin regenerates similarly to normal skin, with 77 genes playing a role in the process.
295 citations
,
June 2009 in “Science” Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.
232 citations
,
October 2015 in “International journal of molecular sciences” Stem cells are crucial for skin repair and new treatments for chronic wounds.
176 citations
,
April 2011 in “Science” Hair stem cell regeneration is controlled by signals that can explain different hair growth patterns and baldness.
87 citations
,
January 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
84 citations
,
January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
65 citations
,
July 2020 in “Science Advances” Dermal exosomes with miR-218-5p boost hair growth by controlling β-catenin signaling.
60 citations
,
July 2011 in “Stem Cells and Development” Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.
50 citations
,
October 1918 in “The journal of experimental zoology” Artificially inducing hair regrowth in mice can change the normal pattern and timing of hair growth, with minimal color differences between old and new fur.