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Basal cell carcinomas in mice can start from hair follicle stem cells and other skin cell types, depending on signaling levels.

A faulty KLHL24 gene leads to hair loss by damaging hair follicle stem cells.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Wounded skin cells can revert to stem cells and help heal.

A small group of slow-growing cells causes basal cell carcinoma to return after treatment.

A protein called IL-36γ causes skin side effects from certain cancer treatments when combined with a common skin bacteria.

Integrin-linked kinase is crucial for melanoblasts to properly colonize the skin.

IFN-γ production by CD4 T cells is crucial for causing alopecia areata.

The transcription factor Meis2 is essential for touch sensation and proper nerve development in touch receptors.

Basal cell carcinomas need extra mutations to grow from small to large tumors.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

HDAC4 and HDAC7 are crucial for Th17 cell development and could be targeted to treat inflammatory diseases.

Caspase-1 helps hair stem cells move to heal wounded or inflamed skin.

Stress can cause hair loss and trigger autoimmunity by damaging hair follicle cells.

Two-photon microscopy helps observe hair follicle stem cell behaviors in mice.

Mouse spermatogenesis shows that stem cells can behave flexibly and move widely in open environments.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Stem cells help heal wounds by rapidly dividing and migrating to the wound edge.

TAF4 is important for skin cell growth and helps prevent skin cancer in mice.

The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.

Gata6 is important for protecting hair growth cells from DNA damage and keeping normal hair growth.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Topical drugs and near-infrared light therapy show potential for treating alopecia.

Certain mature cells in mouse lungs can turn back into stem cells to aid in tissue repair.

Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.

Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.

Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Stem cells are crucial for tissue growth, cancer treatment, and disease modeling, but challenges remain in clinical use.

Careful selection of mice by genetics and age, and controlled housing conditions improve the reliability of hair regrowth in wound healing tests.