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Personalized thiopurine dosing based on NUDT15 genotyping can improve long-term outcomes for ulcerative colitis and Crohn's disease patients.

Benzothiazepines like diltiazem reduce anxiety in mice by making neurosteroids.

Sheep wool follicles absorb different amino acids at various rates and locations, which could affect wool growth based on diet and genetics.

Proactive monitoring and management are essential to maximize the benefits of Trastuzumab Deruxtecan while minimizing serious side effects.

Ethanol changes GABAA receptor α4 subunit levels through phosphorylation and neuroactive steroids.

LAAM caused developmental toxicity in tolerant rats without causing birth defects.

The TG5 gene affects beef cattle weight, and the CC genotype leads to higher weights.

Targeting gut microbiome and metabolome may help treat autoimmune skin diseases like alopecia areata.

Dietary linoleic acid may help reduce hyperthyroidism effects.

The enzyme system in hair follicles is similar to the liver's and is inhibited by certain substances.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Efficient enzyme function relies on specific residue interactions and structural coordination.

Testosterone undecanoate can reduce the negative effects of Finasteride on male reproductive health.

A more sensitive assay was developed to detect enzyme activity converting arginine to citrulline in hair follicles.

A reliable method was developed to measure aristolochic acid-I in rat blood.

Hair follicles have an enzyme that converts arginine to citrulline in proteins.

L-Carnitine-L-tartrate may help hair grow and prevent hair loss.

Stress worsens Tourette symptoms by increasing allopregnanolone levels.

Inhibiting certain enzymes made female rats more sensitive to low-level pain.

Nitrogen starvation in microalgae increases lipid production, making it a potential biofuel source.

Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.

The study created a new method to test drugs that affect hormone processing in skin.

Researchers developed a reliable method to measure testosterone and epitestosterone in urine for medical and anti-doping use.

t-Flavanone may help hair growth by reducing a specific protein's activity in skin cells.

Biotin and biotinidase are essential to prevent health issues, and deficiencies require lifelong supplementation.

The plant hormone auxin activates the TOR pathway, affecting gene expression related to growth and cell size.

Eight blood metabolites are linked to causing allergic conjunctivitis, offering new ways to predict and treat it.