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GlossaryTazarotene

topical retinoid used for treating acne and psoriasis

Tazarotene is a topical medication that belongs to the class of drugs known as retinoids, which are derived from vitamin A. It is commonly used to treat skin conditions like psoriasis and acne by promoting cell turnover and reducing inflammation. For professionals, it's important to note that tazarotene works by modulating gene expression, which helps normalize the differentiation and proliferation of epithelial cells.

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research A single center, pilot, double-blinded, randomized, comparative, prospective clinical study to evaluate improvements in the structure and function of facial skin with tazarotene 0.1% cream alone and in combination with GliSODin® Skin Nutrients Advanced A

9 citations , May 2014 in “Clinical Cosmetic and Investigational Dermatology”

Using tazarotene with GliSODin improves facial skin more than tazarotene alone.

research Adult-onset porokeratotic eccrine ostial and dermal duct nevus:dermatoscopic findings and treatment with tazarotene

7 citations , January 2020 in “Dermatology online journal”

An adult with a rare skin condition improved with tazarotene treatment.

research Referee report. For: Comparison between Tazarotene 0.05% gel and Adapelene 0.1% gel in acne patients [version 1; peer review: 1 approved with reservations]

January 2024 in “Faculty of 1000 Research Ltd”

Tazarotene gel may be more effective for acne than adapalene gel.

research Acne Keloidalis Nuchae Successfully Treated with Halobetasol 0.01% and Tazarotene 0.045% Lotion

July 2022 in “SKIN The Journal of Cutaneous Medicine”

A new lotion with halobetasol and tazarotene successfully treats acne keloidalis nuchae.

research Psoriasis treatment in difficult locations: scalp, nails, and intertriginous areas

104 citations , August 2008 in “Clinics in Dermatology”

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

research Topical Retinoids: Therapeutic Mechanisms in the Treatment of Photodamaged Skin

69 citations , March 2016 in “American journal of clinical dermatology”

Topical retinoids effectively improve photodamaged skin.

research Epidermal Growth Factor Receptor Inhibitors: A Review of Cutaneous Adverse Events and Management

68 citations , January 2014 in “Dermatology research and practice”

Skin side effects from cancer drugs targeting EGFR can affect treatment adherence but can be managed with antibiotics like tetracycline.

research ACNE

58 citations , January 1997 in “Dermatologic Clinics”

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

research Side effects of common acne treatments

38 citations , November 2012 in “Expert Opinion on Drug Safety”

Common acne treatments can cause various side effects, like skin irritation and more serious issues, but combination therapies are often more effective and better tolerated.

Porokeratotic Adnexal Ostial Nevus: Review on the Entity and Therapeutic Approach

research Porokeratotic adnexal ostial naevus: review on the entity and therapeutic approach

23 citations , September 2014 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology”

Laser treatments are the most effective for porokeratotic adnexal ostial nevus.

research ADVANCES IN PSORIASIS THERAPY

20 citations , January 2000 in “Dermatologic Clinics”

New psoriasis treatments are effective but come with side effects and risks.

Comedonal Lupus: A Case Study of a 60-Year-Old Moroccan Man

research Lupus comédonien

7 citations , November 2007 in “Annales de Dermatologie et de Vénéréologie”

A man was diagnosed with a rare form of lupus after showing unique skin symptoms that responded well to treatment.

research KID Syndrome: Report of a Case and Support for Its Reclassification as an Ectodermal Dysplasia

6 citations , May 2000 in “Pediatric Dermatology”

KID syndrome should be reclassified as an ectodermal dysplasia.

research Recent therapeutic developments for acne

5 citations , February 2013 in “Expert Review of Dermatology”

New acne treatments include combination creams, advanced retinoids, and light therapies, focusing on safety and patient adherence.

Scalp Psoriasis: Etiology, Diagnosis, And Treatment

research Psoriasis del cuero cabelludo etiología, diagnóstico y tratamiento

August 2024 in “Polo del Conocimiento”

Scalp psoriasis is treated with topical therapies, phototherapy, and systemic medications.

research Cosmeceuticals

June 2004

Isotretinoin and tazarotene help treat acne, while minoxidil and finasteride promote hair growth.

research IMMEDIATE HYPERSENSITIVITY TO PERMANENT HAIR COLOR: 7

1 citations , June 1999 in “American Journal of Contact Dermatitis”

Tazarotene gel is more effective for acne than tretinoin and works as well as adapalene.

Clinico-Epidemiology of Keratosis Pilaris with Histopathologic and Dermoscopic Evaluation: A Cross-Sectional Study in a Rural Tertiary Hospital

research Clinico-epidemiology of Keratosis Pilaris with Histopathologic and Dermoscopic Evaluation – A Cross-sectional Study in a Rural Tertiary Hospital

April 2026 in “Clinical Dermatology Review”

Keratosis pilaris significantly affects quality of life and shows specific skin changes.

research Increased risk of telogen effluvium with tirzepatide compared to other weight-loss medications: a retrospective cohort TriNetX database study

August 2025 in “Journal of the American Academy of Dermatology”

research Antipsoriatic Activity of a New Synthetic Retinoid

20 citations , September 1983 in “Archives of dermatology”

The new synthetic retinoid RO 13-6298 effectively treated severe psoriasis at low doses with manageable side effects.

research Monilethrix treated with the oral retinoid Ro 10-9359 (Tigason)

24 citations , July 1983 in “Clinical and Experimental Dermatology”

Tigason improved hair growth in a boy with monilethrix without side effects.

research Comparison of efficacy and safety of tofacitinib and azathioprine in patients with alopecia areata and variants: a double-blind, randomized controlled trial

5 citations , July 2024 in “Archives of Dermatological Research”

research Tofacitinib 2% ointment, a topical Janus kinase inhibitor, for the treatment of alopecia areata: A pilot study of 10 patients

48 citations , November 2017 in “Journal of the American Academy of Dermatology”

Tofacitinib 2% ointment helped hair regrow in 3 out of 10 patients with alopecia areata, but caused side effects like scalp irritation and raised cholesterol in some.

research P075 A randomized controlled trial comparing the efficacy and safety of oral tofacitinib vs. methotrexate in moderate-to-severe alopecia areata

June 2025 in “British Journal of Dermatology”

Tofacitinib was more effective than methotrexate for treating alopecia areata.

research Bexarotene gel: A new topical therapy for alopecia areata

4 citations , January 2010 in “International journal of trichology”

Bexarotene gel shows promise as a new treatment for alopecia areata.

research [Oral treatment of severe psoriasis with a new aromatic retinoid (Ro 10-9359) (author's transl)].

12 citations , October 1978 in “PubMed”

Ro 10-9359 is an effective treatment for severe psoriasis but can cause side effects.