January 2022 in “Stem cell biology and regenerative medicine” The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.
66 citations
,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
60 citations
,
June 1997 in “Journal of The American Academy of Dermatology” Apoptosis is crucial for healthy skin and treating skin diseases.
44 citations
,
November 1998 in “Australasian Journal of Dermatology” Accurate diagnosis is key for treating different kinds of hair loss, and immune response variations may affect the condition and treatment results.
23 citations
,
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” NF-κB is crucial for different stages and types of hair growth in mice.
17 citations
,
February 2015 in “International Journal of Molecular Sciences” A special mix from certain skin cells can help hair grow by making hair root cells grow faster and activating growth signals.
10 citations
,
September 2022 in “Advanced Healthcare Materials” Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
6 citations
,
January 2010 in “Springer eBooks” SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.
6 citations
,
July 2009 in “Journal of Cutaneous Pathology” Hair follicle stem cells are key for hair growth and skin repair.
1 citations
,
July 2023 in “Cytotherapy” Magnetic nanovesicles from stem cells can improve hair growth by staying in the skin longer.
Basal cell carcinoma behaves like hair follicles and targeting specific pathways may help treat it.
6 citations
,
October 2007 in “médecine/sciences” Mammals can regenerate new hair follicles from skin stem cells.
January 2025 in “PLoS ONE” Elf5 controls skin cell growth and development, making it a potential target for skin treatments.
Skin stem cells in hair follicles are important for touch sensation.
39 citations
,
May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
277 citations
,
June 2003 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
54 citations
,
January 2016 in “Cell reports” Activating β-catenin in different skin stem cells causes various types of hair growth and skin tumors.
52 citations
,
October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
30 citations
,
December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
6 citations
,
October 2020 in “Frontiers in cell and developmental biology” WWOX deficiency in mice causes skin and fat tissue problems due to disrupted cell survival signals.
3 citations
,
June 2006 in “Expert Review of Dermatology” The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
2 citations
,
September 2023 in “International journal of molecular sciences” Special proteins are important for skin balance, healing, and aging, and affect skin stem cells.
April 2018 in “Journal of Investigative Dermatology” BMP signaling is important for skin color, affecting melanin production, pigment spread, and cell movement.
9 citations
,
June 2016 in “Stem cells” Overexpression of sPLA2-IIA in mouse skin reduces hair stem cells and increases cell differentiation through JNK/c-Jun pathway activation.
August 2025 in “Journal of Investigative Dermatology” Fibronectin is essential for hair follicle regeneration and may help rejuvenate aged skin.
479 citations
,
January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
159 citations
,
December 2007 in “American Journal of Pathology” Stress-related substance P may lead to hair loss and negatively affect hair growth.
90 citations
,
June 2006 in “The American Journal of Dermatopathology” The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.
51 citations
,
July 2010 in “Trends in Endocrinology and Metabolism” Prolactin may play a significant role in skin and hair health and could be a target for treating skin and hair disorders.
47 citations
,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.