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January 2021 in “GeroScience” Spermidine helps protect against aging by preserving telomere length.
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January 2000 in “Journal of Cutaneous Pathology” Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.
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April 2025 in “Science Advances” Loss of Ten1 in mice causes telomere shortening and symptoms similar to human dyskeratosis congenita.
70 citations
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March 2008 in “Mechanisms of Ageing and Development” Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
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May 2022 in “Frontiers in Cell and Developmental Biology” Epigenetic and metabolic changes affect stem cell function and aging in skin.
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September 2019 in “PLOS genetics” Telomere damage affects skin and hair follicle stem cells by messing up important growth signals.
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September 2016 in “Aging Cell” Low selenium levels can extend lifespan but worsen health issues.
April 2017 in “The FASEB journal” Low selenium levels worsen health but increase lifespan in mice.
25 citations
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November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
September 2016 in “Springer eBooks” Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.
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January 2021 in “Journal of Investigative Dermatology” Hair follicle studies suggest that maintaining telomere length could help treat hair loss and graying, but it's uncertain if mouse results apply to humans.
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January 2025 in “Aging and Disease” Lengthening telomeres may reverse aging and extend lifespan.
April 2015 in “The FASEB Journal” Selenium deficiency worsens aging symptoms in mice.
January 2013 in “University Libraries (University of Maryland)” Selenium helps protect cells from aging and damage, especially under stress.
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May 2021 in “Frontiers in aging neuroscience” Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
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March 2022 in “IntechOpen eBooks” Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
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April 2002 in “Medical Hypotheses” Hormones cause hair loss by affecting cell growth and weakening cell attraction.
February 2026 in “Journal of Regenerative Medicine and Biology Research” Exosomes show promise for anti-aging and regenerative treatments.
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December 2011 in “Annales de Dermatologie et de Vénéréologie” 2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
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October 2024 in “Cells” PRP therapy shows promise for anti-aging but lacks consistent evidence and standardization.
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July 2018 in “Frontiers in Neurology” Myotonic dystrophy may be classified as a segmental progeroid disorder.
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February 2021 in “FEBS Journal” Targeting regulatory T cells may help treat age-related diseases.
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October 2021 in “Frontiers in Cell and Developmental Biology” There might be a specific histone code for cellular quiescence, but more research is needed.
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January 2017 in “Dermatologic Surgery” Combining cosmetic procedures with lifestyle changes improves antiaging results.
Testosterone pellet therapy may better address hormone imbalances in aging by focusing on local hormone production and symptom relief.
February 2026 in “Frontiers in Pharmacology” Genetics can help tailor treatments for male pattern hair loss, improving outcomes like stabilization or modest regrowth.
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July 2002 in “Pigment Cell Research” The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.
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January 2018 in “The International Journal of Developmental Biology” Cell aging can be both good and bad for tissue repair.
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February 2017 in “Oncotarget” Cellular senescence has both cancer-blocking and cancer-promoting effects, and targeting senescent cells may improve health and lifespan.