research Isolation and Characterization of Mouse High-glycine/Tyrosine Proteins
Mouse high-glycine/tyrosine proteins have distinct patterns in hair follicles, peaking at specific hair cycle days.
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450-480 / 1000+ resultsresearch Implantation study on the potential of murine epidermal stem cell differentiation
Murine epidermal stem cells can develop into skin structures without rejection when implanted.
research Mediator 1 ablation induces enamel-to-hair lineage conversion through enhancer dynamics
Removing Mediator 1 causes teeth cells to turn into hair cells.
research Progenitor Cell Dynamics in Androgenetic Alopecia: Insights from Spatially Resolved Transcriptomics
Targeting EMT and fibrotic remodeling may help treat androgenetic alopecia.
research In vivo imaging of mammary epithelial cell dynamics in response to lineage-biased Wnt/β-catenin activation
Activating β-catenin in mammary cells leads to changes that cause early-stage abnormal growths similar to skin structures.
research Mesenchyme governs hair follicle induction
The mesenchyme can start hair growth, but the exact signal that causes this is still unknown.
research Lef1 Contributes to the Differentiation of Bulge Stem Cells by Nuclear Translocation and Cross-Talk with the Notch Signaling Pathway
Lef1 helps stem cells become hair cells by interacting with specific signaling pathways.
research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo
Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
research Probing keratinocyte and differentiation specificity of the human K5 promoter in vitro and in transgenic mice.
The K5 promoter controls gene expression in skin cells, with specific DNA segments crucial for targeting and regulation.
research MEF/KSF‑conditioned culture medium: An effective method forin vitroculture of mouse dermal papilla cells with osteogenic differentiation potential
MEF/KSF-conditioned medium effectively grows mouse hair follicle stem cells with bone-forming potential.
research c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research Synthesis of nerve growth factor mRNA in cultures of developing mouse whisker pad, a peripheral target tissue of sensory trigeminal neurons.
A soluble factor in developing mouse whisker pads boosts nerve growth factor mRNA production.
research Transient activation of β-catenin signalling in adult mouse epidermis is sufficient to induce new hair follicles but continuous activation is required to maintain hair follicle tumours
Temporary activation of β-catenin can create new hair follicles, but ongoing activation is needed to keep hair follicle tumors.
research Retinoic Acid-Induced Epidermal Transdifferentiation in Skin
Retinoic acid helps change skin cells and is important for skin development and hair growth.
research Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling
The conclusion is that certain cell interactions and signals are crucial for hair growth and regeneration.
research Yin and yang of hair cells
Activin A increases inner ear hair cell development, while follistatin decreases it.
research 592 Cross-interactions of BMP and WNT signaling pathways attenuate androgen effect on HFSC differentiation
BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.
research Sequences and differential expression of three novel human type-II hair keratins
Hair differentiation starts earlier than thought, involving multiple type-II keratins.
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Also Regeneration after Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research Differentiation genes were governed by DNA methylation during hair follicle morphogenesis in Cashmere goat
DNA methylation controls hair follicle gene expression in cashmere goats.
research Functional analysis of thymosin beta-4 using over-expressing transgenic mice
Melanoma cells lose their ability to form tumors when placed in a zebrafish embryo environment.
research Activation and regulation of the granulation tissue derived cells with stemness-related properties
Granulation tissue-derived cells can aid wound healing and serve as an alternative source of stem cells for tissue repair.
research 195 Androgen action and 3D culture conditions influence dermal papilla cells inductive properties: the role of Wnt agonists/antagonists balance
DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
research Regulation of Keratin Gene Expression in Hair Follicle Differentiationa
Keratin gene regulation is similar across mammals, affecting hair follicle differentiation.
research Wnt-10b promotes differentiation of skin epithelial cells in vitro
Wnt-10b helps skin cells develop into hair-related structures.
research Calcium Regulation of Growth, Differentiation and Keratinization of Cultured Cells from Murine Hair and Hair Follicles : An Ultrastructural Study
research HaCaT‑conditioned medium supplemented with the small molecule inhibitors SB431542 and CHIR99021 and the growth factor PDGF‑AA prevents the dedifferentiation of dermal papilla cells in vitro
A mix of specific inhibitors and a growth factor helps keep hair growth cells from losing their properties in the lab.
research Inducing hair follicle neogenesis by defined extracellular factors
Certain factors can start hair growth in adult skin by making cells communicate and form new hair follicles.
research Faculty Opinions recommendation of Conditional telomerase induction causes proliferation of hair follicle stem cells.
Activating telomerase can boost hair follicle stem cell growth and hair production.
research Epidermal Stem Cells Are Defined by Global Histone Modifications that Are Altered by Myc-Induced Differentiation
Myc changes chromatin in stem cells, causing them to leave their niche.