13 citations
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March 1999 in “Biochemical Journal” Overexpressing SSAT in mice makes them highly sensitive to polyamine analogues, causing liver damage and high mortality.
Finasteride significantly reduced sperm production and caused testicular atrophy in hamsters.
19 citations
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March 2011 in “Cutaneous and Ocular Toxicology” Some chemicals absorbed through the skin can cause serious health problems.
20 citations
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June 1985 in “Toxicologic Pathology” Some steroid-induced health issues in rodents improved after stopping treatment, but hair loss and eye problems did not.
March 2022 in “Oncology Times” Tebentafusp-tebn improves survival rates in uveal melanoma patients but has common side effects like rash and fatigue.
Early NAS level changes affect alcohol consumption vulnerability.
10 citations
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December 2019 in “in Vivo” Testosterone makes the connections in the uterus lining simpler and lowers certain protein levels, which might lead to infertility.
Finasteride and testosterone are the drugs most linked to male infertility, but many other potential drugs may be under-reported.
1 citations
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March 2025 in “Archivos Argentinos de Pediatria” Exposure to certain chemicals in food and containers may increase the risk of early breast development in young girls.
64 citations
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May 2000 in “International Journal of Dermatology” Thalidomide improved lupus symptoms but caused nerve damage in some patients.
June 2025 in “Annals of the Rheumatic Diseases” Pregnant women with rheumatic diseases often have poor nutrition, needing more folic acid, calcium, and iron, while consuming too much selenium.
3 citations
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April 2024 in “JAAD Case Reports” DPCP may be safe for treating alopecia during pregnancy, but more research is needed.
8 citations
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March 2015 in “International Journal of Oncology” Tsc2-deficient stem cells can help understand and treat TSC-related tumors.
April 2017 in “International journal of current advanced research” Pregnant women often have skin changes, but only a small percentage have skin conditions caused by or specific to pregnancy; doctors need to tell them apart for proper treatment.
March 2003 in “BJOG: An International Journal of Obstetrics and Gynaecology” Mothers and newborns with dental fillings have higher mercury in their hair, but adding fillings during pregnancy doesn't raise mercury levels further.
May 2017 in “Journal of The American Academy of Dermatology” An intact skin barrier is crucial to prevent infection in cases of tether-induced tenosynovitis.
January 2011 in “InTech eBooks” Pesticide exposure may increase the risk of hypospadias in males.
108 citations
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November 1980 in “British Journal of Dermatology” Oral retinoids are effective for various skin conditions but have side effects and should not be used during pregnancy.
12 citations
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December 2011 in “Canadian Journal of Microbiology” Serotype 4 of Ureaplasma showed the highest pathogenicity in female mice.
3 citations
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January 1985 in “Acta Obstetricia Et Gynecologica Scandinavica” A rare ovarian tumor caused early puberty signs in a 1-year-old girl, but surgery reduced hormone levels.
147 citations
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April 1997 in “Oncogene” Overexpressing IGF-1 in mice leads to skin abnormalities and tumors.
54 citations
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March 2012 in “International Journal of Andrology” Prenatal pesticide exposure may cause earlier breast development in girls.
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October 1971 in “The BMJ” Anticonvulsant drugs may cause temporary chromosomal abnormalities.
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January 2001 in “Archives of Biochemistry and Biophysics” Activated ras can protect kidney cells from a certain substance that causes cell death.
187 citations
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January 1994 in “The New England Journal of Medicine” Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.
January 1988 in “Toxicological Sciences” 4PeCDF is highly toxic to male rats, causing weight loss, organ damage, and death.
November 2010 in “Clin-Alert” Monitoring for adverse effects in clinical treatments is crucial.
5 citations
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June 2008 in “Acta Cirurgica Brasileira” Finasteride causes sperm production decrease in Mesocricetus auratus.
27 citations
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April 2011 in “Folia Histochemica et Cytobiologica” DHT deficiency can disrupt cell connections in rat testes, possibly affecting fertility.
77 citations
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July 2007 in “Dermatologic Therapy” Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.