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GlossaryTerbinafine

antifungal medication treating skin, hair, and nail infections

Terbinafine, commonly known by the brand name Lamisil, is an antifungal medication used to treat fungal infections of the skin, hair, and nails. It works by inhibiting the enzyme squalene epoxidase, which is essential for the synthesis of ergosterol, a key component of fungal cell membranes, thereby leading to the death of the fungal cells.

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research Determination of the efficacy of terbinafine hydrochloride nail solution in the topical treatment of dermatophytosis in a guinea pig model

51 citations , May 2008 in “Mycoses”

Terbinafine HCl nail solutions with DDAIP HCl are more effective than current treatments for nail infections.

Malassezia Species Overgrowth in a Chinchilla Cat

research Malassezia spp. Overgrowth in a Chinchilla Cat

December 2018 in “DergiPark (Istanbul University)”

The cat's skin condition improved with treatment, but underlying health issues must be addressed.

research Hair loss after terbinafine treatment

3 citations , July 2008 in “British journal of dermatology/British journal of dermatology, Supplement”

Terbinafine can cause hair loss.

research Understanding Microemulsions and Nanoemulsions in (Trans)Dermal Delivery

14 citations , January 2025 in “AAPS PharmSciTech”

Microemulsions and nanoemulsions can effectively deliver drugs through the skin, but more research is needed to understand their differences and mechanisms.

Comparison of Rheological Properties, Follicular Penetration, Drug Release, and Permeation Behavior of a Novel Topical Drug Delivery System and a Conventional Cream

research Comparison of rheological properties, follicular penetration, drug release, and permeation behavior of a novel topical drug delivery system and a conventional cream

34 citations , October 2014 in “European journal of pharmaceutics and biopharmaceutics”

The new drug delivery system releases the drug better in sebum and targets follicles more effectively than the conventional cream.

research NANOEMULGEL AS A RECENT DRUG DELIVERY SYSTEM

8 citations , December 2021 in “Military Medical Science Letters”

Nanoemulgel is a promising method for delivering drugs, especially for those that don't dissolve well in water.

research Nanoemulgels: A new approach for the treatment of skin-related disorders

September 2024 in “International Journal of Pharmaceutical Quality Assurance”

Nanoemulgels improve skin disorder treatment by delivering drugs more effectively and reducing application frequency.

research Herbal Nanocosmeceuticals: The Ultimate Fusion of Science and Nature

January 2024 in “Pharmacophore”

Herbal nanocosmeceuticals are more effective and eco-friendly than traditional skincare products.

Identification of Trichophyton Rubrum by Nested PCR Analysis from Paraffin Embedded Specimen in Trichophytia Profunda Acuta of the Glabrous Skin

research Identification of Trichophyton rubrum by Nested PCR Analysis from Paraffin Embedded Specimen in Trichophytia Profunda Acuta of the Glabrous Skin

23 citations , January 2005 in “Nihon Ishinkin Gakkai zasshi”

Nested PCR can reliably identify fungal infections when traditional methods fail.

research Compilation of a comprehensive gene panel for systematic assessment of genes that govern an individual’s drug responses

13 citations , October 2010 in “Pharmacogenomics”

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

research Formulation And Evaluation Of Emulgel Of An Antifungal Drug For Topical Drug Delivery

3 citations , January 2023 in “Journal of Pharmaceutical Negative Results”

The emulgel with 11.5% oil and 1.75% gelling agent effectively delivers fluconazole topically with improved spreadability and stability.

research Colistin adorned topical nanoemulsion gel formulation for enhanced anti-microbial activity

1 citations , September 2025 in “Scientific Reports”

The new gel improves treatment of tough skin infections.

research Geriatric Dermatologic Therapy

February 2026

Elderly skin care needs personalized treatment, early intervention, and integrated psychiatric care.

research Abstracts

October 2020 in “Veterinary Dermatology”

New treatments and diagnostic methods for various animal skin conditions showed promising results.

research Oral cyclosporin does not arrest progression of androgenetic alopecia

July 2008 in “British Journal of Dermatology”

Cyclosporin doesn't stop hair loss.

research Spectrophotometric and Stability Indicating RP-HPLC-PDA method for Simultaneous Determination of Finasteride and Tamsulosin in Combined Tablet Dosage form

1 citations , December 2009 in “Asian Journal of Research in Chemistry”

The methods accurately measure Finasteride and Tamsulosin in tablets.

research Research-based findings on scope of liposome-based cosmeceuticals: an updated review

13 citations , November 2022 in “Future Journal of Pharmaceutical Sciences”

Liposome-based cosmeceuticals improve treatment effectiveness for skin and hair conditions.

research Nanoemulgel: For Promising Topical and Systemic Delivery

5 citations , April 2022 in “IntechOpen eBooks”

Nanoemulgel is a better way to deliver drugs through the skin for various conditions.

research Subject Index

February 2009 in “Journal of the American Academy of Dermatology”

research Solid Lipid Nanoparticles for Drug Delivery: Pharmacological and Biopharmaceutical Aspects

559 citations , October 2020 in “Frontiers in Molecular Biosciences”

Solid lipid nanoparticles are promising for safe and effective drug delivery but need more research for clinical use.

research Formulation-by-Design of Efinaconazole Spanlastic Nanovesicles for Transungual Delivery Using Statistical Risk Management and Multivariate Analytical Techniques

25 citations , July 2022 in “Pharmaceutics”

Spanlastic nanovesicles can improve efinaconazole delivery through nails.

research Development, Optimization, and In Vitro/In Vivo Evaluation of Azelaic Acid Transethosomal Gel for Antidermatophyte Activity

19 citations , April 2023 in “Antibiotics”

Azelaic acid in a special gel is more effective against skin fungi than regular azelaic acid.

research A Full Factorial Design to Optimize Aminexil Nano Lipid Formulation to Improve Skin Permeation and Efficacy Against Alopecia

12 citations , January 2023 in “AAPS PharmSciTech”

research Impact of Formulation Variables on Meloxicam spanlastics Preparation

3 citations , December 2024 in “Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512)”

Spanlastics are effective for delivering Meloxicam with improved stability and targeting.

research Transethosomes: A Comprehensive Review of Ultra-Deformable Vesicular Systems for Enhanced Transdermal Drug Delivery

January 2025 in “AAPS PharmSciTech”

Transethosomes improve drug delivery through the skin and show promise for treating various conditions.

Terbinafine Levels in Serum, Stratum Corneum, Dermis-Epidermis, Hair, Sebum, and Eccrine Sweat

research Terbinafine levels in serum, stratum corneum, dermis-epidermis (without stratum corneum), hair, sebum and eccrine sweat.

121 citations , January 1991 in “Acta dermato-venereologica”

Terbinafine quickly builds up in skin and hair, staying effective for over 3 weeks.

research Case Report. Kerion Celsi effectively treated with terbinafine. Characteristics of kerion Celsi in the elderly in Japan

6 citations , November 1999 in “Mycoses”

A man in Japan got better from a scalp fungal infection using terbinafine.