86 citations
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May 2002 in “Journal of Investigative Dermatology” A new keratin, hK6irs1, is found in all layers of the hair follicle's inner root sheath.
56 citations
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September 2013 in “Experimental Dermatology” The guide explains how to study human and mouse sebaceous glands using various staining and imaging techniques, and emphasizes the need for standardized assessment methods.
118 citations
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January 2016 in “Current Topics in Developmental Biology” The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.
36 citations
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July 2014 in “Experimental Dermatology” Skin and hair can regenerate after injury due to changes in gene activity, with potential links to how cancer spreads. Future research should focus on how new hair follicles form and the processes that trigger their creation.
47 citations
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December 2003 in “Journal of Investigative Dermatology” DS cells in hair follicles can help form and restore hair, especially in hair loss conditions.
23 citations
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July 2018 in “Journal of Cosmetic Dermatology” Chemotherapy caused hair loss with specific patterns, but most patients had hair regrowth after treatment, while some had lasting hair loss.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
January 1997 in “Elsevier eBooks” Hair and nails are skin parts that develop early and serve protective and functional roles.
Sensory neuron remodeling and Merkel-cell changes happen independently during skin maintenance.
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
Sensory neuron changes and Merkel-cell changes in the skin happen independently during normal skin maintenance.
Sensory neurons and Merkel cells remodel at different rates during normal skin maintenance.
Sensory neuron remodeling and Merkel-cell changes in the skin happen independently.
Sensory neuron and Merkel-cell changes in the skin happen independently during normal skin maintenance.
April 2025 in “Cellular and Molecular Biology” Human dermal stem/progenitor cells can divide and differentiate more than hair follicle dermal papilla cells.
June 2021 in “Research Square (Research Square)” The exact identity of skin stem cells and how skin cells differentiate is not fully known.
Sensory neuron and Merkel cell changes in the skin happen independently during normal skin maintenance.
7 citations
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October 2024 in “Cells” Autophagy is essential for proper skin cell development and function.
16 citations
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September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
19 citations
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August 2012 in “Cell death and differentiation” Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.
51 citations
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February 2009 in “Journal of dermatological science” Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.
45 citations
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December 2014 in “Journal of the European Academy of Dermatology and Venereology” Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.
23 citations
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January 1986 Involucrin is crucial for skin cell maturation and protection.
November 2015 in “Hair transplant forum international” Early attempts at using cloned cells for hair transplants failed, but 3D cell growth showed some promise.
1 citations
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December 2023 Hair grows in cycles and changes with age, starting from fetal development.
3 citations
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May 2018 in “Journal of Cosmetic Dermatology” Biopsy can differentiate between alopecia areata and androgenic alopecia, and if more information is needed, testing for CD3 and CD8 can help.
98 citations
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August 2007 in “PLoS ONE” Myc changes chromatin in stem cells, causing them to leave their niche.
31 citations
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May 2019 in “Nature communications” Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
March 2022 in “Indian Journal of Animal Research” Dog hair follicle stem cells can turn into fat cells.