research Non-competitive androgen receptor inhibition in vitro and in vivo
Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.
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810-840 / 1000+ results research A comparison of the cytotoxic effects of fatty acids on in vitro breast and prostate cell lines
DHA derivatives, especially didocosahexaenoin, effectively kill prostate cancer cells and may offer a safer cancer treatment option.
research Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance
TRPM5 is crucial for maintaining hair growth.
research Synthesis of 11α-hydroxyprogesterone hartens
Researchers successfully made new compounds for hormone level tests, but one attempt led to an unexpected product, correcting a past error.
research Synthesis and biological evaluation of 3-tetrazolo steroidal analogs: Novel class of 5α-reductase inhibitors
3-tetrazolo steroidal analogs can strongly inhibit the enzyme linked to hair loss.
research Optimasi Kombinasi Ramuan Etnomedisin Penumbuh Rambut Nusa Tenggara Timur menggunakan Orthogonal Stimulus Response Method pada %Kepadatan Rambut Mencit (Mus Musculus)
The formula significantly boosts hair growth and density.
research Biosynthesis of Dihydrotestosterone by a Pathway that Does Not Require Testosterone as an Intermediate in the SZ95 Sebaceous Gland Cell Line
Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.
research Small Molecule Wnt Pathway Modulators from Natural Sources: History, State of the Art and Perspectives
Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors/Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research Elucidating penetration pathways into the hair fiber using novel microscopic techniques.
The conclusion is that substances can penetrate hair fibers through multiple pathways, including both the cell membrane complex and the non-keratinous parts.
research Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Metabolic pathways of eicosanoids—derivatives of arachidonic acid and their significance in skin
Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.
research Table 2_Computational drug discovery of potential 5α-reductase phytochemical inhibitors and hair growth promotion using in silico techniques.xlsx
Jamogenin and other molecules from plants may help treat hair loss.
research Determination of cantharidin,nitrogen mustard and minoxidil in nurturing hair products by liquid chromatography-tandem mass spectrometry
research Atroposelective Synthesis of Biaryl N‐Oxides via Cu‐Catalyzed De Novo Heteroaromatic N‐Oxide Ring Formation
A new method efficiently creates biaryl N-oxides with potential for cancer treatment and drug development.
research Resveratrol derivatives: a patent review (2009 – 2012)
New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
research Screening of synthetic and natural product databases: Identification of novel androgens and antiandrogens
Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
research Pharmacological activities of Tridax procumbens (Asteraceae)
Tridax procumbens has medicinal properties.
research Identification of bioactive compounds from thai plant extracts with hair growth promoting activity on human hair dermal papilla cells
Thai plant extracts, especially Avicennia marina, can promote hair growth by inhibiting certain enzymes and boosting growth factors.
research Pharmacognostical standardization of bark of Thuja orientalis Linn.
The study concluded that standardizing Thuja orientalis bark helps in its identification and quality control.
research Synthesis and Structure–Activity Relationships of the First Ferrocenyl-Aryl-Hydantoin Derivatives of the Nonsteroidal Antiandrogen Nilutamide
Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.
research Studi Molecular Docking Aktivitas Anti Alopecia pada Senyawa yang Terkandung dalam Daun Dadap Serep (Erythrina subumbrans (Hassk.) Merrill)
Erythrina subumbrans leaves may help treat hair loss.
research FeCl3-catalysed C-N coupling reaction between cyclic ethers and heterocyclic amines
Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.
research Natural Sources of Therapeutic Agents Used in Skin Conditions
Bee venom, fig, and geranium oil can effectively treat skin conditions and are safer alternatives to some conventional drugs.
research Tea Tree Oil Concentration in Follicular Casts After Topical Delivery: Determination by High-Performance Thin Layer Chromatography Using a Perfused Bovine Udder Model
Different tea tree oil mixtures absorb into hair follicles at varying levels, with microemulsion being the most effective.
research GC-MS Fatty Acid Profile and In silico Studies of Telfairia occidentalis Hook f. (Fluted Pumpkin) and Sphenostylis stenocarpa (African Yam bean) Seeds Oil on Human 5 Alpha Reductase II
Compounds in fluted pumpkin and African yam bean seed oils may help manage benign prostate hyperplasia.
research Preparation and application of tea-seed saponin modified silicone polymer quaternary ammonium salt
The compound improves hair conditioning in shampoos.
research Human androgenic steroids affect growth of dermatophytes in vitro
Androgenic steroids can slow down or stop the growth of certain skin fungi.
research Trapa bispinosa Roxb. Pericarp Extract Exerts 5α-Reductase Inhibitory Activity in Castrated Benign Prostatic Hyperplasia Model Mice
Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.
research The influence of selected steroid hormones on the physicochemical behaviour of DPPC liposomes
Steroid hormones change the size, charge, and stability of DPPC liposomes.