Finasteride reduces DHT levels and affects gene expression in fish, similar to its effects in humans.
November 2022 in “Journal of the Endocrine Society” Removing the ovarian tumor improved the woman's hormonal symptoms.
8 citations
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April 2016 in “Experimental Dermatology” The type of tumor suppressor affects the form of skin cancer from hair follicle stem cells.
January 2004 in “Banca y finanzas: Revista profesional de gestión financiera” Androgens increase pigmentation in certain hamster skin areas, but estrogens can reverse this effect.
3 citations
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April 2019 in “Human & Experimental Toxicology” Finasteride causes harmful organ changes in female mice.
23 citations
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January 2017 in “BMC Medical Genetics” A new CDH3 gene mutation was found in a Spanish patient with sparse hair and eye issues.
3 citations
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July 2022 in “Brain and Behavior” The HtrA1L364P mutation causes brain dysfunction and blood vessel damage.
9 citations
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August 2013 in “PLOS ONE” Genetic variants at 20p11 increase baldness risk in Chinese Han people.
72 citations
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November 2012 in “PloS one” The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.
July 2024 in “Indian Journal of Dermatology Venereology and Leprology” Certain gene variations in PITX2 are linked to a higher risk of male pattern baldness in Indians.
176 citations
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August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.
Bicalutamide does not significantly affect liver enzymes and is a safe anti-androgen option for transfeminine individuals.
10 citations
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January 2019 in “Journal of the American Academy of Dermatology” Testosterone increases hair growth and acne in transgender men.
1 citations
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October 2022 in “Curēus” Diagnosing simple-virilizing congenital adrenal hyperplasia can be difficult and requires thorough testing and expert advice.
15 citations
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August 2010 in “Fertility and sterility” Metformin works better for adolescent girls with PCOS who have certain genetic variations.
2 citations
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June 2023 in “Journal of cell science” Mutations in iRhom2 affect hair and skin in mice and are linked to esophageal cancer, with ADAM17 playing a crucial role.
1 citations
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December 2022 in “BMC Genomics” The Msx2 gene affects feather development in Hungarian white geese and a specific gene variation could indicate feather quality.
6 citations
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January 2003 in “Dermatology” Men with X-linked recessive ichthyosis often experience male-pattern baldness.
2 citations
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October 2020 in “Annals of Oncology” Men may be more vulnerable to severe COVID-19 due to genetic and hormonal factors, but more research is needed.
35 citations
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April 1998 in “PubMed” Activated erbB-2 in mice skin causes severe skin and hair abnormalities.
January 1994 in “JAPANESE JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS” Testosterone and fleece-flower root affect mouse hair growth.
April 2026 in “BMJ Case Reports” Leydig cell tumors can cause high testosterone in women and are treated by removing the ovaries.
November 2020 in “International journal of contemporary pediatrics” Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.
68 citations
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February 2019 in “Urology” Hormonal treatment in transgender women reduces semen quality, but stopping treatment may improve it.
1 citations
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October 2023 in “Frontiers in endocrinology” Regulating certain sex hormones may help delay facial aging.
April 2020 in “Journal of the Endocrine Society” Male pattern baldness may indicate arterial stiffness in transgender men on long-term testosterone therapy.
Combined finasteride and anastrozole therapy effectively treats BPH, influenced by hormone imbalances and genetics.
4 citations
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January 1982 in “Endocrinologia Japonica” Androgens regulate 5 alpha-reductase activity in hamster sebaceous glands.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” A girl with excessive hair growth had a genetic change on chromosome 17 that reduced the activity of two genes linked to hair growth.
September 2023 in “Journal of The American Academy of Dermatology” Hormone therapy in transgender and gender diverse individuals affects hair loss differently than in cisgender individuals.