1 citations
,
February 2016 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” An 84-year-old woman's hair loss was due to a rare condition called Leydig cell hyperplasia, which was treated with surgery.
28 citations
,
November 2017 in “Molecular and cellular endocrinology” Testosterone and its byproducts help support male sexual behavior through different pathways in the brain and body.
15 citations
,
June 1986 in “Pediatric Dermatology” Androgens increase pigmentation in young hamsters, but estrogens can reverse this effect.
19 citations
,
June 1997 in “The Journal of Clinical Endocrinology & Metabolism” The treatment successfully lowered testosterone levels and reduced symptoms.
1 citations
,
August 2023 in “Case Reports in Women s Health” Leydig cell hyperplasia can cause virilization in postmenopausal women and is treatable with surgery.
6 citations
,
April 2019 in “Endocrinology and Metabolism Clinics of North America” Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.
59 citations
,
September 2003 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
April 2014 in “The FASEB Journal” Testosterone reduces knee movement, while flutamide and finasteride increase it.
2 citations
,
August 2011 in “Revista Medica De Chile” A postmenopausal woman's high testosterone levels and symptoms improved after removing a tumor from her ovary.
21 citations
,
October 2011 in “British Journal of Dermatology” Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.
April 2017 in “The journal of sexual medicine” 5-alpha-reductase inhibitors significantly affect the penile tissue of hypertensive rats.
October 2019 in “European heart journal” Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.
35 citations
,
January 2012 in “The Journal of Sexual Medicine” Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.
7 citations
,
January 2017 in “Indian Journal of Dermatology, Venereology and Leprology” 13 citations
,
September 2013 in “Steroids” The DHT immunoassay is unreliable due to high cross-reactivity with testosterone.
15 citations
,
May 1986 in “Journal of the American Veterinary Medical Association” Castration helped a dog with a tumor and hair loss by normalizing hormone levels and regrowing hair.
10 citations
,
January 1997 in “The journal of sex research/The Journal of sex research” Testosterone replacement therapy significantly improved sexual interest and function in HIV+ men.
January 2026 in “JCEM Case Reports” Benign conditions can mimic serious ones in postmenopausal hyperandrogenism, requiring careful diagnosis.
August 2012 in “Open Repository and Bibliography (University of Liège)” A castrated dog developed hair loss and prostate issues from long-term exposure to estrogen cream.
10 citations
,
September 2015 in “Folia Histochemica Et Cytobiologica” Finasteride treatment in male rats can reduce fertility and affect sperm development in their offspring.
10 citations
,
March 2019 in “Journal of neuroendocrinology” Testosterone affects stress hormone levels differently in adolescent and adult male rats.
2 citations
,
May 2018 in “Journal of The American Academy of Dermatology” Hypothyroidism patients with hair loss typically have thinning hair, smaller hair follicles, and normal hair shedding.
2 citations
,
January 2017 in “Endocrinology” Testosterone and its metabolites have varied effects on different body systems, especially during puberty.
October 2023 in “Journal of the Endocrine Society” A woman's ovarian fibroma caused high testosterone levels, which normalized after surgery.
9 citations
,
November 2013 in “Gynecological Endocrinology” A woman had high testosterone due to an ovarian issue, which was fixed with surgery.
April 2023 in “Research Square (Research Square)” A 24-year-old woman had a rare ovarian tumor that caused male-pattern hair growth and was hard to diagnose and treat.
April 2020 in “Journal of the Endocrine Society” A rare ovarian tumor that produced testosterone caused a blood clot in the lungs and increased red blood cells in a woman.
October 2025 in “Journal of the Endocrine Society” Anastrozole can cause increased testosterone, leading to symptoms like hair growth and thinning.
35 citations
,
October 2011 in “Medicine and science in sports and exercise” Muscles can make their own androgens, which may help muscle growth.
June 2007 in “Endocrinology and Metabolism Clinics of North America” The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.