December 2024 in “Quality in Sport” Hormonal balance is vital for women's health and performance, but therapies like contraceptives and steroids have both benefits and risks.
55 citations
,
March 1990 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride may treat baldness but less effective for those with 5α-reductase deficiency.
94 citations
,
August 2002 in “Experimental Dermatology” 17α-estradiol boosts aromatase activity in female hair follicles, potentially helping with hair loss.
40 citations
,
October 2004 in “Veterinary Dermatology” Trilostane treatment led to full hair regrowth in most Pomeranians and all miniature poodles with alopecia X.
129 citations
,
January 2004 in “Journal of medicinal chemistry” Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.
Cyproterone acetate is an effective treatment for women with acne, hair loss, and excessive hair growth.
18 citations
,
March 2010 in “Gynecologic and obstetric investigation” The oral contraceptive alone is the preferred treatment for hirsutism, as adding the GnRH analog showed no significant benefit.
14 citations
,
February 2018 in “Psychoneuroendocrinology” Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
3 citations
,
November 2022 in “Separations” The method accurately measures seven androgens in plasma and shows different hormone levels in females with acne and obesity.
10 citations
,
February 2017 in “European journal of neuroscience/EJN. European journal of neuroscience” The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.
October 2022 in “Springer eBooks” The document concludes that personalized hormonal treatments are important for transgender individuals and more research is needed for non-binary treatments.
16 citations
,
August 2007 in “Histopathology” A woman's rare adrenal tumor caused high testosterone and cortisol levels, which normalized after the tumor was removed.
2 citations
,
January 2022 in “Skin Pharmacology and Physiology” Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.
18 citations
,
August 1985 in “European journal of endocrinology” Cyproterone acetate is effective for treating hirsutism, but some patients may feel worse on low-dose maintenance therapy.
6 citations
,
August 1996 in “The Journal of Clinical Endocrinology and Metabolism” MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.
1 citations
,
January 2020 in “Elsevier eBooks” Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.
2 citations
,
October 1988 in “Steroids” Certain hormone treatments can increase SBP levels and help with mild body hair growth.
31 citations
,
October 1971 in “Steroids” Human beard hair follicles change testosterone into other related hormones, but don't much change androstenedione into testosterone.
September 2025 in “Clinical Cosmetic and Investigational Dermatology” Many people in Jordan misuse topical steroids without proper knowledge, highlighting the need for better education and regulation.
October 2019 in “European heart journal” Androgen-deprivation therapies increase the risk of certain heart conditions, but testosterone treatment may help.
31 citations
,
April 2016 in “Journal of the American Academy of Dermatology” Oral dexamethasone may help regrow hair in adults with alopecia totalis and universalis.
5 citations
,
November 2015 in “Journal of Enzyme Inhibition and Medicinal Chemistry” Certain derivatives are more effective 5α-reductase type 2 inhibitors than finasteride.
10 citations
,
October 2012 in “Andrology” Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
54 citations
,
May 2015 in “Endocrinology” Manipulating 5α-reductase type 2 can affect liver fat production and glucocorticoid effects.
1 citations
,
February 1971 in “JAMA” Triamcinolone acetonide helps scalp grafts grow hair successfully.
76 citations
,
December 1997 in “Fertility and Sterility” Finasteride reduces hair growth better, but spironolactone has more side effects.
22 citations
,
January 2008 in “Physiological Research” Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
1 citations
,
June 1987 in “British journal of dermatology/British journal of dermatology, Supplement” Most patients tolerated spironolactone for acne and hirsutism despite common side effects like menstrual changes and breast tenderness.
July 2011 in “مجله علمی پزوهشی دانشگاه علوم پزشکی ایلام” Testosterone reduces, while finasteride enhances, morphine's pain relief.
49 citations
,
June 1998 in “Journal of Endocrinological Investigation” Cyproterone acetate plus ethinyl estradiol is generally more effective in treating hirsutism, but consider side effects and patient characteristics.