research The Double Edge Sword of Testosterone’s Role in the COVID-19 Pandemic
Testosterone may influence COVID-19 severity and outcomes.
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research Effects of lifelong testosterone exposure on health and disease using Mendelian randomization
Higher testosterone levels can increase the risk of certain diseases like type 2 diabetes in women and prostate cancer in men, but can also protect against autoimmune diseases and hair loss. It also affects body fat and bone density.
research Sex hormone-binding globulin and saliva testosterone levels in men with androgenetic alopecia
Men with hair loss have lower SHBG and higher saliva testosterone levels, suggesting increased androgen activity.
research CHRONIC TREATMENT REGIMENS FOR HIRSUTISM IN WOMEN: EFFECT ON BLOOD PRODUCTION RATES OF TESTOSTERONE AND ON HAIR GROWTH
Combination therapy significantly reduces testosterone and moderately reduces hair growth in women with hirsutism.
research The rationale for physiological testosterone replacement in women
Testosterone replacement may help post-menopausal women with androgen insufficiency, but more research is needed on its benefits and risks.
research Sexual dimorphism of growth plate prehypertrophic and hypertrophic chondrocytes in response to testosterone requires metabolism to dihydrotestosterone (DHT) by steroid 5‐alpha reductase type 1
Male cells need DHT to respond to testosterone, while female cells do not.
research Hair growth promoting effect of white wax and policosanol from white wax on the mouse model of testosterone-induced hair loss
White wax and policosanol from white wax effectively reduced hair loss and promoted hair growth in mice better than a known hair growth drug.
research Prescribing testosterone and DHEA: The role of androgens in women
Testosterone and DHEA can benefit women's health but must be prescribed carefully due to potential risks.
research Cognitive effects of testosterone and finasteride administration in older hypogonadal men.
Testosterone improves mood and thinking skills; finasteride has no effect.
research Testosterone metabolites differentially maintain adult morphology in a sexually dimorphic neuromuscular system
Androgens are essential for maintaining adult neuromuscular structure.
research Testosterone levels in relation to oral contraceptive use and the androgen receptor CAG and GGC length polymorphisms in healthy young women
Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.
research Testosterone therapy in men: Clinical and pharmacological perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research Mitotic activity in the epidermis of the rabbit stimulated with local applications of testosterone propionate
Testosterone applied to rabbit skin increases skin cell growth and changes skin structure.
research Testosterone-stimulated weanlings as an alternative to castrated male rats in the Hershberger anti-androgen assay
Using testosterone-stimulated weanling rats can effectively replace castrated rats for anti-androgen testing, reducing animal stress.
research Testosterone protects female embryonic heart H9c2 cells against severe metabolic stress by activating estrogen receptors and up-regulating IES SUR2B
Testosterone protects female heart cells from stress by activating estrogen receptors.
research Testosterone and the Brain: From Cognition to Autism
Testosterone affects brain functions and contributes to sex differences, influencing conditions like autism.
research Testosterone in COVID-19: An Adversary Bane or Comrade Boon
Testosterone's effects on COVID-19 are unclear and need more research.
research Steroidomics for highlighting novel serum biomarkers of testosterone doping
Monitoring steroid hormones in blood can better detect testosterone doping.
research Testosterone Induces Increase in Aquaporin (AQP)-1, 5, and 7 Expressions in the Uteri of Ovariectomized Rats
Testosterone increases certain proteins in the uterus, reducing fluid volume.
research Different patterns of 5α-reductase expression, cellular distribution, and testosterone metabolism in human follicular dermal papilla cells
Androgen effects on hair follicles vary by skin area.
research Torilin fromTorilis japonica,as a New Inhibitor of Testosterone 5α-Reductase
Torilin from Torilis japonica can inhibit testosterone 5α-reductase but is less effective than finasteride.
research In vitro effects of testosterone, dihydrotestosterone and estradiol on cell growth of human hair bulb papilla cells and hair root sheath fibroblasts.
High levels of testosterone and dihydrotestosterone inhibit hair cell growth, while high levels of estradiol promote it.
research Testosterone target therapy: focus on immune response, controversies and clinical implications in patients with COVID-19 infection
Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
research Improvement in scalp hair growth in androgen‐deficient women treated with testosterone: a questionnaire study
Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.
research Testosterone implants in women: Pharmacological dosing for a physiologic effect
Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
research Abietic Acid from Resina Pini of Pinus Species as a Testosterone 5.ALPHA.-Reductase Inhibitor
Abietic acid from pine resin can effectively inhibit testosterone 5α-reductase.
research Contraception Care for Transmasculine Individuals on Testosterone Therapy
Transmasculine individuals on testosterone therapy need tailored contraception and fertility advice due to unique risks and benefits of each contraceptive method.
research Long-Term Suppression of Testosterone After Treatment with a Gonadotropin-Releasing Hormone Agonist in a Woman with a Presumed Testosterone Secreting Ovarian Tumor
The treatment successfully lowered testosterone levels and reduced symptoms.
research Inhibition of Hair Growth by Testosterone in the Presence of Dermal Papilla Cells from the Frontal Bald Scalp of the Postpubertal Stumptailed Macaque
Testosterone can slow hair growth in adult monkeys, but a blocker called RU 58841 can counteract this and potentially help hair regrow.
research Uncovering the complex relationship between balding, testosterone and skin cancers in men
Men with baldness are more prone to skin cancers on the scalp due to sun exposure, not testosterone.