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Blocking androgen activity in newborn rats affects body weight and appetite-related hormones differently in males and females.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

Androgens like testosterone may help treat traumatic brain injury by reducing mitochondrial stress and inflammation.

Jagged1 and Epidermal Growth Factor together significantly increased hair growth in mice with androgen-suppressed hair.

A new microneedle patch helps treat hair loss by improving drug delivery to hair follicles.

Hormones like androgens, estrogen, thyroid hormones, and stress hormones can contribute to hair loss, and treatments target these hormonal imbalances.

Letrozole reduces seizures but not brain damage in mice.

The paper concludes that animal models help in understanding hair loss causes and developing new treatments.

Testosterone stimulates growth in intermediate hair follicles, but this can be blocked by cyproterone acetate.

CRH promotes fat production in skin cells, affecting conditions like acne.

Natural antioxidants like flavonoids and resveratrol may help prevent low testosterone in aging men.

Men with more CAG repeats in the androgen receptor gene and lower testosterone levels may experience more severe COVID-19.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

Melatonin may improve some hormonal and inflammatory issues in women with PCOS.

Sex steroids produced in the hippocampus are crucial for brain functions like memory and learning in rodents.

Current murine models need improvement for better human wound healing research translation.

5α-reductase inhibitors may reduce male fertility and could be used for male contraception.

Androgens and estrogens are crucial for male reproductive health, affecting hormone levels and tissue function.

Oral estradiol works for many transgender women but needs personalized dosing and monitoring.

Muscles can make their own androgens, which may help muscle growth.

PCOS is linked to inflammation, and certain markers could help in its treatment.

Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Sex hormones may affect COVID-19 severity, with estrogen possibly reducing risk and testosterone potentially increasing it.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

Sex steroids, especially progesterone, can slow down the growth of mouse melanoma cells.

About 19.4% of Iranian women in the study have Polycystic Ovary Syndrome, with the most common type involving irregular periods and high male hormone levels, but their heart and metabolic health is similar to women without the condition.