research Evaluation of 5α-reductase inhibitory activity of certain herbs useful as antiandrogens
Some herbs show promise as antiandrogenic agents.
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research Cardiovascular risk factors and events in women with androgen excess
Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.
research Effect of finasteride, a 5 alpha-reductase inhibitor, on serum gonadotropins in normal men.
Finasteride doesn't affect hormone levels in normal men.
research Relative Safety and Efficacy of Finasteride for Treatment of Hirsutism
Finasteride reduces hirsutism effectively with fewer side effects but is a second-choice treatment due to safety concerns.
research Androgen antagonists in androgen target tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Targeted transfollicular delivery of artocarpin extract from Artocarpus incisus by means of microparticles
Microparticles containing artocarpin extract could effectively treat hair loss and acne with minimal side effects.
research The antiandrogenic effect of finasteride against a mutant androgen receptor
Finasteride may improve prostate cancer treatment outcomes.
research A comparative study of Aldactone® and Diane® in the treatment of hirsutism
Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.
research 5α‐Reductase Inhibitors
Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.
research Therapeutic options in the polycystic ovary syndrome
The document suggests various treatments for PCOS, including medication for menstrual issues, insulin resistance, and excess hair, as well as fertility treatments, while highlighting the need for personalized care and lifestyle changes.
research An intergenerational androgenic mechanism of female intrasexual competition in the cooperatively breeding meerkat
Androgens in female meerkats influence aggression and dominance, affecting social dynamics and offspring behavior.
research The Use of Trilostane for the Treatment of Alopecia X in Alaskan Malamutes
Trilostane effectively treated hair loss in Alaskan Malamutes with no adverse effects.
research Inhibition of steroid 5 alpha-reductase with finasteride: sleep-related erections, potency, and libido in healthy men.
Finasteride doesn't affect erections much, but may decrease libido in men.
research Does Finasteride Have a Preventive Effect on Chronic Bacterial Prostatitis? Pilot Study Using an Animal Model
Finasteride may help prevent chronic bacterial prostatitis, with better results when combined with antibiotics.
research Finasteride for prostatic disease: an updated and comprehensive review
Finasteride helps treat prostate issues and may prevent prostate cancer in high-risk men.
research Long-Term Response of Hirsutism and Other Hyperandrogenic Symptoms to Combination Therapy in Polycystic Ovary Syndrome
Combination therapy with oral contraceptives and spironolactone improves hair growth, menstrual issues, and acne in women with PCOS.
research The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific
Dutasteride and finasteride affect different cell types differently.
research Enzyme-linked immunosorbent assays for doping control of 5α-reductase inhibitors finasteride and dutasteride
New tests detect finasteride and dutasteride in urine quickly and easily.
research Research Brief: Self-Reports of a Constellation of Persistent Antiandrogenic, Estrogenic, Physical, and Psychological Effects of Finasteride Usage Among Men
Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.
research Increased DHT levels in androgenic alopecia have been selected for to protect men from prostate cancer
Higher DHT in male baldness may protect against prostate cancer.
research Proscar@ (Finasteride) inhibits 5α-reductase activity in the ovaries and testes of Lytechinus variegatus Lamarck (Echinodermata: Echinoidea)
Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.
research Screening of Euphorbiaceae Plant Extracts for Anti-5α-reductase
Phyllanthus urinaria extract may help treat hair loss by blocking a hair-related enzyme.
research Chapter 23. Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research Severe scalp hair loss in a female patient with acromegaly treated with lanreotide autogel after unsuccessful surgery
A woman with acromegaly experienced severe hair loss from a drug called Lanreotide Autogel, which improved after stopping the treatment.
research Clascoterone as a novel treatment for androgenetic alopecia
Clascoterone may be a promising treatment for hair loss.
research Synthesis and bioactivity of new Finasteride conjugate
New Finasteride conjugate improves prostate treatment and vital signs in rats.
research Comparison of Finasteride, Metformin, and Finasteride Plus Metformin in PCOS
Finasteride and metformin both help treat PCOS, but using them together works best.
research Should Finasteride Be Routinely Given Preoperatively for TURP?
Finasteride may reduce bleeding after TURP, but more research needed.
research Variations in anterior segment parameters among different phenotypes of polycystic ovary syndrome
PCOS may increase eye pressure and corneal thickness, affecting eye health.
research Treatment of idiopathic facial hirsutism with medroxyprogesterone acetate iontophoresis
Medroxyprogesterone acetate iontophoresis safely and effectively reduces facial hair growth in women.