10 citations
,
April 2006 in “Seminars in Reproductive Medicine” Testosterone therapy may improve mood, well-being, and sexual function in premenopausal women, but more research is needed on its long-term safety and effectiveness.
8 citations
,
February 2009 in “Current Women's Health Reviews” Testosterone treatment can improve sexual function and bone density in women but may have adverse effects and requires more research on safety and guidelines.
7 citations
,
May 2012 in “International Journal of Andrology” The new oral testosterone pill normalized testosterone levels and lowered SHBG in men with low testosterone.
6 citations
,
January 2020 in “The Aging Male” Testosterone replacement therapy improved blood sugar and fat levels without raising prostate cancer risk in Japanese men with low testosterone.
6 citations
,
November 2010 in “International Journal of Andrology” New oral testosterone formulations show potential for safer, effective hormone replacement in men with low testosterone.
5 citations
,
August 2018 in “Sexual Medicine Reviews” 5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
5 citations
,
June 2004 in “The Journal of The British Menopause Society” Testosterone therapy can improve sexual satisfaction and mood in surgically menopausal women when used with estrogen, but its long-term safety and effects on naturally menopausal and premenopausal women are unclear.
September 2023 in “Biology of reproduction” New testosterone analogs show promise for male contraception with better activity and potentially fewer side effects.
January 2003 in “Journal für Kardiologie (Krause & Pachernegg GmbH)” Testosterone therapy can improve skin and hair in men with low testosterone but may cause skin irritation with certain treatments.
110 citations
,
October 2013 in “The Journal of Sexual Medicine” Testosterone treatment in trans men increases body and facial hair and may lead to hair loss over time, but severe skin issues are rare.
37 citations
,
February 2013 in “Maturitas” Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.
December 2016 in “The Journal of Sexual Medicine” Short-acting testosterone injections in a clinic are a preferred treatment for low testosterone because they work well, are convenient, and patients stick with the treatment.
9 citations
,
February 2020 in “International Journal of Endocrinology” Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.
4 citations
,
November 2024 in “International Journal of Dermatology” Testosterone use for muscle growth can cause hair loss in males.
204 citations
,
May 2014 in “The Journal of Sexual Medicine” Hormone therapy for trans individuals is effective and generally safe in the short term.
146 citations
,
December 2016 in “Translational Andrology and Urology” Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.
57 citations
,
January 2004 in “Journal of Endocrinology” Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.
1 citations
,
January 2020 in “Elsevier eBooks” Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.
855 citations
,
June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
658 citations
,
June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
166 citations
,
October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
122 citations
,
November 2014 in “BMC Medicine” Oral testosterone therapy raises heart risk more than other methods.
110 citations
,
April 2002 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Dihydrotestosterone gel improved well-being and sexual function in older men without negatively affecting prostate health.
99 citations
,
June 1999 in “The Journal of Clinical Endocrinology and Metabolism” Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.
77 citations
,
June 2015 in “Nature Reviews Urology” Some common medications can harm male fertility, but many effects can be reversed.
77 citations
,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
66 citations
,
October 2013 in “Current Opinion in Endocrinology, Diabetes and Obesity” The conclusion is that published guidelines are improving transgender medical care, but more research and education in transgender medicine are needed.
63 citations
,
January 2010 in “Frontiers in Aging Neuroscience” 3α-androstanediol helps reduce age-related cognitive and mood declines in male rats, unlike testosterone.
51 citations
,
April 1999 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.
45 citations
,
March 2015 in “Clinical Endocrinology” Testosterone therapy is generally safe for transmen, improves sexual function, and has manageable health risks with proper monitoring.