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GlossaryTetracycline

antibiotic that inhibits bacterial protein synthesis

Tetracycline is a type of antibiotic used to treat a variety of bacterial infections. It works by inhibiting the protein synthesis of bacteria, effectively stopping their growth and reproduction. This class of antibiotics is commonly used for conditions like acne, urinary tract infections, and certain types of respiratory infections.

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research Conditional Gene Expression in the Epidermis of Transgenic Mice Using the Tetracycline-Regulated Transactivators tTA and rTA Linked to the Keratin 5 Promoter

215 citations , November 2000 in “Journal of Investigative Dermatology”

The system allows precise control of gene expression in mouse skin, useful for studying skin biology.

The Human Hair Follicle as Sentinel for Drug Evaluation: Demonstration of Tetracycline Adhesion to Hair Follicle as Proposed Mechanism in Dysfunctional Hair Loss

research THE HUMAN HAIR FOLLICLE AS SENTINEL FOR DRUGS EVALUATION: DEMONSTRATION OF TETRACYCLINE ADHESION TO HAIR FOLLICLE AS PROPOSED MECHANISM IN DYSFUNCTIONAL HAIR LOSS

4 citations , December 2020 in “International journal of research - granthaalayah”

Tetracycline can stick to hair follicles and potentially cause hair loss.

Successful Treatment of Iatrogenic Cutaneous Calcification by Tetracycline in a Labrador Retriever

research Successful treatment of iatrogenically developed cutaneous calci-fication by tetracycline in labrador retriever

January 2020 in “Animal Husbandry Dairy and Veterinary Science”

Tetracycline successfully treated a Labrador's skin calcification and hair loss.

research Reduction of oral tetracycline of lipolysis of triglycerides in hair lipid

1 citations , January 1980 in “Acta Dermato Venereologica”

Oral tetracycline reduces fat breakdown in hair lipids.

research Spurious Tetracycline Fluorescence in Hair

3 citations , May 1964 in “Nature”

research Synergistic Effect of Co-Delivering Ciprofloxacin and Tetracycline Hydrochloride for Promoted Wound Healing by Utilizing Coaxial PCL/Gelatin Nanofiber Membrane

67 citations , February 2022 in “International Journal of Molecular Sciences”

The nanofiber membranes effectively promote wound healing and have strong antibacterial properties.

research Acne, the Skin Microbiome, and Antibiotic Treatment

134 citations , January 2019 in “American journal of clinical dermatology”

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Primary Cicatricial Alopecia: Treatment Approaches and Classification

research Primary cicatricial alopecia

95 citations , November 2016 in “Journal of The American Academy of Dermatology”

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

research Prevention and management of dermatological toxicities related to anticancer agents: ESMO Clinical Practice Guidelines☆

86 citations , November 2020 in “Annals of Oncology”

Early intervention and tailored management can reduce skin side effects from cancer treatments.

Folliculitis Decalvans: A Multicenter Review of 82 Patients

research Folliculitis decalvans: a multicentre review of 82 patients

68 citations , February 2015 in “Journal of the European Academy of Dermatology and Venereology”

Early onset and pustules indicate severe hair follicle inflammation, and while antibiotics help, the condition often worsens after treatment stops.

research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne

65 citations , February 2009 in “The journal of investigative dermatology/Journal of investigative dermatology”

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

research S2k guideline for the treatment of hidradenitis suppurativa / acne inversa – Short version

41 citations , May 2024 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft”

The guideline recommends using specific drugs and surgery together for treating hidradenitis suppurativa effectively.

Folliculitis Decalvans: Effectiveness of Therapies and Prognostic Factors in a Multicenter Series of 60 Patients with Long-Term Follow-Up

research Folliculitis decalvans: Effectiveness of therapies and prognostic factors in a multicenter series of 60 patients with long-term follow-up

41 citations , June 2018 in “Journal of The American Academy of Dermatology”

Some treatments for folliculitis decalvans work well, with tetracyclines and a mix of rifampicin and clindamycin being most effective.

research An Update on Medical Treatment Options for Hidradenitis Suppurativa

36 citations , December 2015 in “Drugs”

New treatments for a chronic skin condition show promise, but individualized plans are crucial due to varying responses.

research Black women’s hair: the main scalp dermatoses and aesthetic practices in women of African ethnicity

32 citations , August 2015 in “Anais Brasileiros de Dermatologia”

Black women's unique hair characteristics and styling practices can lead to specific scalp conditions, which require early diagnosis and appropriate treatment.

research Commentary: Treatment of lichen planopilaris

23 citations , January 2010 in “Journal of The American Academy of Dermatology”

Effective treatments for lichen planopilaris are unclear due to inconsistent results and a lack of strong research evidence.

research Clinical and microscopic features of generalized discoid lupus erythematosus in dogs (10 cases)

20 citations , October 2016 in “Veterinary dermatology”

Dogs with generalized discoid lupus erythematosus have similar symptoms to humans and need continuous treatment.

research Infertility and teratogenicity after paternal exposure to systemic dermatologic medications: A systematic review

18 citations , October 2018 in “Journal of The American Academy of Dermatology”

Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.

research Central centrifugal cicatricial alopecia

11 citations , January 2013 in “Indian Dermatology Online Journal”

CCCA is a common, progressive hair loss condition that may not always be linked to hair care practices and requires a biopsy for diagnosis.

research Safety Considerations and Monitoring in Patients Treated with Systemic Medications for Acne

10 citations , January 2016 in “Dermatologic Clinics”

Some acne medications have side effects; doctors should educate patients and may not need to do frequent lab tests for all.

Use of Spironolactone in Dermatology: Acne, Hidradenitis Suppurativa, Female Pattern Hair Loss, and Hirsutism

research Uso de la espironolactona en dermatología: acné, hidradenitis supurativa, alopecia femenina e hirsutismo

9 citations , June 2020 in “Actas Dermo-Sifiliográficas”

Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.

research Tufted hair folliculitis: complete enduring response after treatment with rifampicin

9 citations , January 2004 in “Journal of dermatological treatment”

Rifampicin effectively treated tufted hair folliculitis with no relapse after one year.

research Pathological Mechanisms Involved in Epidermolysis Bullosa Simplex: Current Knowledge and Therapeutic Perspectives

9 citations , August 2024 in “International Journal of Molecular Sciences”

Promising treatments for EBS include anti-inflammatory drugs, antibiotics, creams, mTOR inhibitors, and gene editing, but more trials are needed.

research Concurrent follicular dysplasia and interface dermatitis in Boxer dogs

9 citations , June 2003 in “Veterinary dermatology”

Boxer dogs may have a genetic skin condition that worsens seasonally and can be treated with certain medications.

research Safety of Common Medications for Treating Dermatology Disorders in Pregnant Women

7 citations , September 2013 in “Current Dermatology Reports”

Some skin medications are safe for pregnant women, but others pose risks or should not be used.

research Management of hidradenitis suppurativa

4 citations , June 2002 in “Clinical and experimental dermatology”

Effective treatment for hidradenitis suppurativa varies, with antibiotics commonly used and surgery as an option, but no single method is universally successful.

research Journal of Pigmentary Disorders

3 citations , March 2019 in “Journal of Pigmentary Disorders”

Clascoterone and minocycline are effective acne treatments with quick results and fewer side effects.

Acne in Adult Women: A Study at Ibn Rochd University Hospital

research Acne in adult women

3 citations , July 2011 in “Journal of the Egyptian Women's Dermatologic Society (Print)”

Acne is common in adult women, often continues from adolescence, and can lead to scarring.

Acne in Children: Presentation and Treatment Overview

research Acne in children

3 citations , March 2011 in “Informa Healthcare eBooks”

Acne in children varies by age and severity, requires a pediatric treatment approach, and may need diagnostic evaluation for underlying conditions.

research Vulvar Fordyce adenitis: A cohort of 45 women

2 citations , July 2021 in “Annales De Dermatologie Et De Venereologie”

Vulvar acne, also known as "vulvar Fordyce adenitis", is a condition causing painful bumps on the labia, and it's not always effectively treated with common acne medications, but isotretinoin has shown promise.